1. Signaling Pathways
  2. GPCR/G Protein
  3. Protease Activated Receptor (PAR)
  4. PAR2 Isoform

PAR2

 

PAR2 Related Products (13):

Cat. No. Product Name Effect Purity
  • HY-P1308
    SLIGRL-NH2
    Agonist 99.78%
    SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2).
  • HY-112558
    AZ3451
    Antagonist 99.60%
    AZ3451 is a potent protease-activated receptor-2 (PAR2) antagonist with IC50 of 23 nM.
  • HY-P1314
    2-Furoyl-LIGRLO-amide
    Agonist 99.87%
    2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0..
  • HY-120261
    GB-88
    Inhibitor 99.05%
    GB-88 is an oral, selective non-peptide antagonist of PAR2, inhibits PAR2 activated Ca2+ release with an IC50 of 2 µM.
  • HY-120528A
    GB-110 hydrochloride
    Agonist 99.83%
    GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM.
  • HY-P1260A
    FSLLRY-NH2 TFA
    Inhibitor 99.43%
    FSLLRY-NH2 TFA is a protease-activated receptor 2 (PAR2) inhibitor.
  • HY-123617
    AZ8838
    Antagonist 98.87%
    AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2.
  • HY-117793
    I-191
    Antagonist 99.38%
    I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist.
  • HY-124748A
    ENMD-1068 hydrochloride
    Antagonist 98.56%
    ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 hydrochloride reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. ENMD-1068 hydrochloride also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 hydrochloride can be used in the study of endometriosis and liver fibrosis.
  • HY-124061
    GB83
    Antagonist
    GB83 is a potent PAR2 antagonist. GB83 reverses neutrophil elastase‐induced synovitis and pain. GB83 blocks the effect of MET-1 supernatant on NG neurons.
  • HY-P1314A
    2-Furoyl-LIGRLO-amide TFA
    Agonist
    2-Furoyl-LIGRLO-amide TFA is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0..
  • HY-P1310A
    VKGILS-NH2 TFA
    Agonist
    VKGILS-NH2 TFA is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 TFA has no effect on DNA synthesis in cells.
  • HY-P1308A
    SLIGRL-NH2 TFA
    Agonist
    SLIGRL-NH2 TFA (Protease-Activated Receptor-2 Activating Peptide TFA) is an agonist of Protease-Activated Receptor-2 (PAR-2).