1. GPCR/G Protein
  2. Protease-Activated Receptor (PAR)
  3. ENMD-1068 hydrochloride

ENMD-1068 hydrochloride 

Cat. No.: HY-124748A
Handling Instructions

ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist with antiangiogenic and anti-inflammatory activities. ENMD-1068 hydrochloride reduces epatic stellate cells (HSCs) activation and collagen expression through the inhibiton of TGF-β1/Smad signal transduction.

For research use only. We do not sell to patients.

ENMD-1068 hydrochloride Chemical Structure

ENMD-1068 hydrochloride Chemical Structure

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Description

ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist with antiangiogenic and anti-inflammatory activities. ENMD-1068 hydrochloride reduces epatic stellate cells (HSCs) activation and collagen expression through the inhibiton of TGF-β1/Smad signal transduction[1][2].

Molecular Weight

319.87

Formula

C₁₅H₃₀ClN₃O₂

SMILES

O=C(N1CCN(C(CC(C)C)=O)CC1)CCCCCN.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

ENMD-1068ENMD1068ENMD 1068Protease-Activated Receptor (PAR)Thrombin receptorsPAR2antiangiogenicanti-inflammatoryIL-6NF-κBanti-proliferationMCP-1Inhibitorinhibitorinhibit

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Product Name:
ENMD-1068 hydrochloride
Cat. No.:
HY-124748A
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