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AY77

AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release.

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  • CAS No.: 1835734-92-3
  • Formula: C21H32N4O4
  • Molecular Weight:404.50
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AY77 Chemical Structure
    AY77 Chemical Structure
CAS No.: 1835734-92-3
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Top Publications Citing

Use of MCE Products

All Protease Activated Receptor (PAR) Isoforms

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  • AY77 Chemical Structure
    AY77 Chemical Structure
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  • AY77