1. GPCR/G Protein
  2. Protease-Activated Receptor (PAR)
  3. GB-110

GB-110 

Cat. No.: HY-120528
Handling Instructions

GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM.

For research use only. We do not sell to patients.

GB-110 Chemical Structure

GB-110 Chemical Structure

CAS No. : 1252806-70-4

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Description

GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM[1].

IC50 & Target

Protease activated receptor 2[1]

Molecular Weight

608.77

Formula

C₃₃H₄₈N₆O₅

CAS No.

1252806-70-4

SMILES

O=C(C1=CC=NO1)N[[email protected]@H](CC2CCCCC2)C(N[[email protected]@H]([[email protected]@H](C)CC)C(NCC3=CC=CC(C(N4CCC(CN)CC4)=O)=C3)=O)=O

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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GB-110
Cat. No.:
HY-120528
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