2. Signaling Pathways
  3. Immunology/Inflammation
  4. Salt-inducible Kinase (SIK)
  5. SIK3 Isoform
  6. SIK3 Inhibitor

SIK3 Inhibitor

SIK3 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-120877
    MRT199665
    		Inhibitor 99.73%
    MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively.
  • HY-120856
    ARN-3236
    		Inhibitor 98.60%
    ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), with IC50s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively.
  • HY-N1570
    Pterosin B
    		Inhibitor 99.32%
    Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling.