SIK2/3-IN-3
SIK2/3-IN-3 (Example 15) is a potent, selective SIK2/3 inhibitor that exhibits preferential inhibitory activity against SIK2 (IC50 = 10.3 nM) and SIK3 (IC50 = 0.8 nM) over SIK1 (IC50 = 801 nM). SIK2/3-IN-3 can be used for the study of inflammatory diseases.
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- CAS. Nr.: 3069526-08-2
- Formel: C24H20N8O2
- Molecular Weight:452.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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SIK1 801 nM (IC50) |
SIK2 10.3 nM (IC50) |
SIK3 0.8 nM (IC50) |
Chemical Information
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CAS. Nr. 3069526-08-2
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Molecular Weight 452.47
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Formel C24H20N8O2
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SMILES
CC(N=N1)=CC=C1OC2=CN3N=CC(C(N=C4N5C(C)=CC(C#N)=N5)=CC=C4[C@H](C)O)=C3C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)