SIK2/3-IN-3
SIK2/3-IN-3 (Example 15) is a potent, selective SIK2/3 inhibitor that exhibits preferential inhibitory activity against SIK2 (IC50 = 10.3 nM) and SIK3 (IC50 = 0.8 nM) over SIK1 (IC50 = 801 nM). SIK2/3-IN-3 can be used for the study of inflammatory diseases.
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- CAS No.: 3069526-08-2
- Formule: C24H20N8O2
- Masse moléculaire:452.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
SIK1 801 nM (IC50) |
QIK/SIK2 10.3 nM (IC50) |
QSK/SIK3 0.8 nM (IC50) |
Chemical Information
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CAS No. 3069526-08-2
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Masse moléculaire 452.47
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Formule C24H20N8O2
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SMILES
CC(N=N1)=CC=C1OC2=CN3N=CC(C(N=C4N5C(C)=CC(C#N)=N5)=CC=C4[C@H](C)O)=C3C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SIK2/3-IN-3 Related Classifications
HY-182804 Related Classifications
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