3069526-08-2
3069526-08-2
Chemical Structure
SIK2/3-IN-3
- CAS No.: 3069526-08-2
- Formula:C24H20N8O2
- Molecular Weight:452.47
InChIKey: NRFMSUMAESDHQD-INIZCTEOSA-N
SMILES: CC(N=N1)=CC=C1OC2=CN3N=CC(C(N=C4N5C(C)=CC(C#N)=N5)=CC=C4[C@H](C)O)=C3C=C2
Biological Activity: SIK2/3-IN-3 (Example 15) is a potent, selective SIK2/3 inhibitor that exhibits preferential inhibitory activity against SIK2 (IC50 = 10.3 nM) and SIK3 (IC50 = 0.8 nM) over SIK1 (IC50 = 801 nM). SIK2/3-IN-3 can be used for the study of inflammatory diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SIK2/3-IN-3 | SIK2/3-IN-3 (Example 15) is a potent, selective SIK2/3 inhibitor that exhibits preferential inhibitory activity against SIK2 (IC50 = 10.3 nM) and SIK3 (IC50 = 0.8 nM) over SIK1 (IC50 = 801 nM). SIK2/3-IN-3 can be used for the study of inflammatory diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
