SIK2/3-IN-1
SIK2/3-IN-1 (Compound 7S) is a selectively inhibitory agent of SIK2/3 with oral activity. SIK2/3-IN-1 can significantly inhibit tumor growth (without any body weight loss) in the MV4-11 AML mice CDX model. SIK2/3-IN-1 can be used in the research of MEF2C-dependent acute myeloid leukemia.
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- CAS No.: 3038863-24-7
- 화학식: C20H19F3N6O2
- 분자량:432.40
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
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QIK/SIK2 |
QSK/SIK3 |
Chemical Information
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CAS No. 3038863-24-7
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분자량 432.40
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화학식 C20H19F3N6O2
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SMILES
O=C1N(CCC2=CC(C3=C(N=CC(C4=CN(N=C4)C)=C3)N)=NC(OC)=C12)CC(F)(F)F
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)