3038863-24-7
3038863-24-7
Chemical Structure
SIK2/3-IN-1
- CAS No.: 3038863-24-7
- Formula:C20H19F3N6O2
- Molecular Weight:432.40
InChIKey: CHHWWKMJOARNHH-UHFFFAOYSA-N
SMILES: O=C1N(CCC2=CC(C3=C(N=CC(C4=CN(N=C4)C)=C3)N)=NC(OC)=C12)CC(F)(F)F
Biological Activity: SIK2/3-IN-1 (Compound 7S) is a selectively inhibitory agent of SIK2/3 with oral activity. SIK2/3-IN-1 can significantly inhibit tumor growth (without any body weight loss) in the MV4-11 AML mice CDX model. SIK2/3-IN-1 can be used in the research of MEF2C-dependent acute myeloid leukemia[1].
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SIK2/3-IN-1 | SIK2/3-IN-1 (Compound 7S) is a selectively inhibitory agent of SIK2/3 with oral activity. SIK2/3-IN-1 can significantly inhibit tumor growth (without any body weight loss) in the MV4-11 AML mice CDX model. SIK2/3-IN-1 can be used in the research of MEF2C-dependent acute myeloid leukemia. | |||||||||||||||||||||
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