1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0301R
    Bifonazole (Standard)
    Bifonazole (Standard) is the analytical standard of Bifonazole. This product is intended for research and analytical applications. Bifonazole (Bay H-4502) is an imidazole antifungal agent.
    Bifonazole (Standard)
  • HY-162957
    LasR-IN-5
    LasR-IN-5 (compound 3C) is a LasR antagonist with an IC50 of 1.37 μM, demonstrating a 77% inhibition of biofilm formation in Pseudomonas aeruginosa. LasR-IN-5 also exhibits quorum sensing (QS) inhibition activity and has potential applications in Pseudomonas aeruginosa infection research.
    LasR-IN-5
  • HY-W423010
    Cefazedone sodium
    Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria.
    Cefazedone sodium
  • HY-76260R
    Faropenem sodium (Standard)
    Faropenem sodium (Standard) is the analytical standard of Faropenem sodium. This product is intended for research and analytical applications. Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.
    Faropenem sodium (Standard)
  • HY-N14248
    Melithiazole A
    Melithiazol A is an antibiotic. Melithiazole A is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal and cytotoxic agent.
    Melithiazole A
  • HY-136821
    Polymyxin D2
    Polymyxin D2 is an antibiotic discovered from Bacillus polymyxa, exhibiting antibacterial activity. Its core structure consists of a cyclic heptapeptide moiety and a tripeptide side chain with a fatty acyl residue. Polymyxin D2 can be used in anti-infective research.
    Polymyxin D2
  • HY-N14851
    Napsamycin C
    Napsamycin C is an antibiotic. Napsamycin C has antibacterial activity against Pseudomonas aeruginosa and other pseudomonas, but has weak antibacterial activity against other Gram-positive and negative bacteria.
    Napsamycin C
  • HY-B0975R
    Penicillin V Potassium (Standard)
    Penicillin V (Potassium) (Standard) is the analytical standard of Penicillin V (Potassium). This product is intended for research and analytical applications. Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis.
    Penicillin V Potassium (Standard)
  • HY-B1407R
    Phthalylsulfathiazole (Standard)
    Phthalylsulfathiazole (N4-Phthalylsulfathiazole) Standard is the analytical standard of Phthalylsulfathiazole (HY-B1407). This product is intended for research and analytical applications. Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is an orally active sulfonamide intestinal antibacterial agent. Phthalylsulfathiazole has low toxicity and excellent bacteriostatic efficacy. Phthalylsulfathiazole inhibits E. coli, streptococci, staphylococci, and total fecal bacteria. Phthalylsulfathiazole can be used in research related to intestinal infections such as colon infection, bacillary dysentery, and ulcerative colitis.
    Phthalylsulfathiazole (Standard)
  • HY-17395R
    Terbinafine hydrochloride (Standard)
    Terbinafine hydrochloride (Standard) is the analytical standard of Terbinafine hydrochloride. This product is intended for research and analytical applications. Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Terbinafine hydrochloride (Standard)
  • HY-B0357A
    Diclazuril potassium
    Diclazuril (R-64433) potassium, a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril potassium can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
    Diclazuril potassium
  • HY-17452AS
    Cefditoren pivoxil-d3
    Cefditoren Pivoxil-d3 (Cefditoren pivoxyl-d3) is deuterium labeled Cefditoren Pivoxil. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections.
    Cefditoren pivoxil-d<sub>3</sub>
  • HY-N14185
    Asparenomycin C
    Asparenomycin C is a carbapenem antibiotic with strong β-lactamase inhibition activities.
    Asparenomycin C
  • HY-126695
    Altromycin B
    Altromycin B is a member of the pluramycin antibiotic family isolated from South African bush soil. Altromycin B shows selective antibacterial activity against Gram-positive bacteria and has in vivo activity against P388 leukemia, colon cancer, lung cancer, and ovarian cancer.
    Altromycin B
  • HY-126735
    Saquayamycin D
    Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC50 of 0.15 and 0.15 μg/mL.
    Saquayamycin D
  • HY-N2306R
    Aclacinomycin A (Standard)
    Aclacinomycin A (Standard) is the analytical standard of Aclacinomycin A. This product is intended for research and analytical applications. Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis.
    Aclacinomycin A (Standard)
  • HY-N14523
    Gilvusmycin
    Gilvusmycin is an antibiotic with strong anti-tumor activity. Gilvusmycin can inhibit P388, K562, A431 and MKN28 cells with IC50s (ng/mL) of 0.08, 0.86, 0.72 and 0.75, respectively.
    Gilvusmycin
  • HY-N14374
    Mycoplanecin B
    Mycoplanecin B is a cyclic peptide antibiotic.
    Mycoplanecin B
  • HY-N14768
    O-Demethylpaulomycin A
    O-Demethylpaulomycin A is an antibiotic with antibacterial activity. O-Demethylpaulomycin A can inhibit Gram-positive bacteria, especially Staphylococcus aureus.
    O-Demethylpaulomycin A
  • HY-N14183
    Asparenomycin B
    Asparenomycin B is a carbapenem antibiotic with strong β-lactamase inhibition activities.
    Asparenomycin B

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