2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic
  5. Antibiotic Activator

Antibiotic Activator

Antibiotic Isoform Comparison

Antibiotic Activator (1):

Cat. No. Product Name Effect Purity
  • HY-B0368B
    D-Captopril
    		Activator
    D-Captopril is a NDM-1 inhibitor and a competitive BlaB inhibitor, with an IC50 value of 21.8 µM against NDM-1 and a Ki of 70-100 µM against BlaB. D-Captopril synergistically reduces the minimum inhibitory concentration of Meropenem (HY-13678) against NDM-1-expressing bacteria. D-Captopril binds to BcII via its thiolate sulfur atom and carboxylate group, altering metal ion occupancy and modulating Cd2+ binding affinity. D-Captopril can be used in the research of neonatal meningitis, sepsis and bacterial infections.