396731-20-7
Chemical Structure
ent-Avibactam sodium
Synonym(s): AVE1330A
- CAS No.: 396731-20-7
- Formula:C7H10N3NaO6S
- Molecular Weight:287.23
IUPAC Name: sodium (1S,2R,5S)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
InChIKey: RTCIKUMODPANKX-UYXJWNHNSA-M
SMILES: NC([C@@H]1[N@]2C(N([C@@H](CC1)C2)OS(=O)(O[Na])=O)=O)=O
Biological Activity: Ent-Avibactam sodium (AVE1330A) is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), ent-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of ent-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ent-Avibactam sodium | Ent-Avibactam sodium (AVE1330A) is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), ent-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of ent-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
