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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Art. -Nr. Produktname Wirkung Reinheit Chemical Structure
  • HY-113621B
    Ageladine A dihydrochloride
    Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values.
    Ageladine A dihydrochloride
  • HY-D2840B
    FITC-mPEG750
    FITC-mPEG750 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG750 can be used for fluorescent labeling and imaging.
    FITC-mPEG750
  • HY-D1795
    Vari Fluor 532 SE
    Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 532 SE
  • HY-D2249
    DiSulfo-ICG maleimide
    DiSulfo-ICG maleimide is a fluorescent dye.
    DiSulfo-ICG maleimide
  • HY-153480E
    Cy3 labled ARC19499 sodium
    Cy3 labled ARC19499 sodium is a Cy3 labled ARC19499 sodium.
    Cy3 labled ARC19499 sodium
  • HY-D1352
    Sulfo-Cyanine7 NHS ester potassium
    Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
    Sulfo-Cyanine7 NHS ester potassium
  • HY-D1061
    2,4,5,6-Tetraaminopyrimidine
    2,4,5,6-Tetraaminopyrimidine is a coloring agent extracted from patent US20170258692A1, compound A.
    2,4,5,6-Tetraaminopyrimidine
  • HY-D2895H
    RB-PEG10000-NH2
    RB-PEG10000-NH2 (Rhodamine B-PEG10000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm).
    RB-PEG10000-NH2
  • HY-179080A
    FITC-DEAE-Polysucrose 400
    FITC-DEAE-Polysucrose 400 is FITC-labeled DEAE-Polysucrose 400. FITC-DEAE-Polysucrose 400 is mainly used for permeability and microcirculation studies (Ex/Em = 488/525 nm).
    FITC-DEAE-Polysucrose 400
  • HY-D2999
    NIR-RED ATP Probe
    NIR-RED ATP Probe is a NIR-II fluorescent probe. NIR-RED ATP Probe exhibits high affinity and selectivity for ATP and can non-invasively and with high contrast detect changes in ATP concentration at the cellular level, with minimal interference to the abundant biomolecules within the cells. NIR-RED ATP Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI).
    NIR-RED ATP Probe
  • HY-D3179
    CDg13
    CDg13 is a fluorescent probe that specifically detects living neural stem/progenitor cells. CDg13 localizes to the endoplasmic reticulum via its dihexyl moiety, with no interaction with endoplasmic reticulum biomolecules. CDg13 undergoes selective efflux by active ABCG2 transporters, with increased intracellular accumulation following ABCG2 inhibition or knockdown. CDg13 isolates and enriches self-renewable neural stem/progenitor cells from embryonic mouse brain tissue, stains neural stem/progenitor cells brightly, and sorts ABCG2low cell populations from heterogeneous populations. (Ex/Em = 520/553 nm)
    CDg13
  • HY-D2322
    SupraFlipper 31
    SupraFlipper 31 is a fluorescent probe. SupraFlipper 31 can be released in the membrane of interest (MOI) via chemical stimulation.
    SupraFlipper 31
  • HY-140877
    Dde Biotin-PEG4-TAMRA-PEG4 Alkyne
    Dde Biotin-PEG4-TAMRA-PEG4 Alkyne is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Dde Biotin-PEG4-TAMRA-PEG4 Alkyne contains Alkyne groups that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Dde Biotin-PEG4-TAMRA-PEG4 Alkyne
  • HY-D1399
    Kdn probe-1
    Kdn probe-1 is a fluorescent Kdn probe and reveals the localization of AfS in vesicles at the cell surface.
    Kdn probe-1
  • HY-114958
    RH 421
    RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase.
    RH 421
  • HY-163140
    BODIPY-phenyl-amide-alkyne
    BODIPY-phenyl-amide-alkyne (compound 6) is an alkyne-containing OFF-to-ON fluorophore. BODIPY-phenyl-amide-alkyne is a BODIPY derivative that can be conjugated to protein IL-33 Y143azidoPhe via CuAAC reaction.
    BODIPY-phenyl-amide-alkyne
  • HY-D1465
    Alexa 532
    Alexa 532 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Alexa 532
  • HY-D1426
    Di-12-ANEPPQ
    Di-12-ANEPPQ is a fast-responding membrane potential dye. Di-12-ANEPPQ, the lipophilic dye, shows cell-specific loading and Golgi-like staining patterns with minimal background fluorescence in the slices of neocortex and hippocampus.
    Di-12-ANEPPQ
  • HY-D1596B
    (E)-Cyanine 3.5 chloride
    (E)-Cyanine 3.5 ((E)-Cy3.5 NHS ester) chloride is a cyanine dye functionalized with a N-hydroxysuccinimide (NHS) group. (E)-Cyanine 3.5 chloride contains NHS groups that react with ammonia to form ester bonds (Ex/Em = 586/612 nm).
    (E)-Cyanine 3.5 chloride
  • HY-177626C
    FAM labled Diranersen sodium
    FAM labled Diranersen sodiumis a FAM labled Diranersen sodium.
    FAM labled Diranersen sodium
Art. -Nr. Produktname / Synonyms Application Reactivity