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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W760183
    EM12-SO2F
    		99.15%
    EM12-SO2F is a powerful covalent inhibitor of CRBN through binding at His353. EM12-SO2F is a useful chemical probe to investigate the CRBN. EM12-SO2F inhibits the degradation of IKZF1 by lenalidomide (HY-A0003) in MOLT4 cells
    EM12-SO2F
  • HY-118262
    Resorufin acetate
    		98.04%
    Resorufin acetate is a fluorescent dye that selectively detects hydrazine.
    Resorufin acetate
  • HY-D0278
    Pigment red 170
    Pigment Red 170 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.
    Pigment red 170
  • HY-D2268A
    QM-FN-SO3 ammonium
    QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission.
    QM-FN-SO3 ammonium
  • HY-D2377
    F8
    		98.25%
    F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels.
    F8
  • HY-112624F1
    CY5-Dextran (MW 4000)
    CY5-Dextran (MW 4000) is a fluorescent dye CY5 (HY-D0821)-labeled Dextran (HY-112624). Dextran-CY5 (MW 4000) can be used to visualize the specific subcellular distribution of dextran at the nanoscale.
    CY5-Dextran (MW 4000)
  • HY-P3106
    (Z-Ala-Ala-Ala-Ala)2Rh110
    (Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.
    (Z-Ala-Ala-Ala-Ala)2Rh110
  • HY-D1076
    DiIC16(3)
    		99.34%
    DiIC16(3) is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins.
    DiIC16(3)
  • HY-D1254
    Trx-red
    Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm).
    Trx-red
  • HY-D0505A
    Eosin Y disodium
    		98%
    Eosin Y disodium (Acid Red 87) is a soluble acid red dye molecule. Eosin Y disodium has a wide application in organic synthesis as a photoredox catalyst.
    Eosin Y disodium
  • HY-D2500
    CY7 DBCO chloride
    		98.05%
    CY7 DBCO chloride is a dye derivative of CY7 (HY-D0825) bearing a DBCO group. CY7 DBCO chloride is a click chemistry reagent. CY7 DBCO chloride contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    CY7 DBCO chloride
  • HY-114907
    4',5'-Dibromofluorescein
    4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis.
    4',5'-Dibromofluorescein
  • HY-133536
    PA Janelia Fluor® 549, SE
    		98.2%
    PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm.
    PA Janelia Fluor® 549, SE
  • HY-W040269
    Dehydrothio-p-toluidine
    		99.91%
    Dehydrothio-p-toluidine (DHPT) is a chemical intermediate used in dyestuff production. Dehydrothio-p-toluidine shows inhalation toxicity in acute and subchronic conditions.
    Dehydrothio-p-toluidine
  • HY-D2593
    Cy7.5-PEG2000-DSPE
    Cy7.5-PEG2000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG2000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
    Cy7.5-PEG2000-DSPE
  • HY-D1719
    Cypate
    		98.60%
    Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging.
    Cypate
  • HY-W151629A
    Ferrozine sodium hydrate
    		99.80%
    Ferrozine sodium hydrate is a spectrophotometric reagent for iron, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm.Ferrozine sodium hydrate-based colorimetric assays can quantify iron in cells
    Ferrozine sodium hydrate
  • HY-171995
    Rf470 TFA
    Rf470 (Rotor NO.4) TFA is a FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently incorporated into peptidoglycan by bacteria. Rf470 TFA has extremely weak fluorescence in the free state, but its fluorescence is significantly enhanced when it is catalytically incorporated into peptidoglycan by transpeptidases. Through fluorescence changes, Rf470 TFA can be used for real-time monitoring of peptidoglycan biosynthesis, detection of transpeptidase activity, and screening of antibiotics, etc.
    Rf470 TFA
  • HY-D2874
    6-AF488 tyramide
    		99.68%
    6-AF488 tyramide is a bright, green fluorescent dye (Ex=496 nm, Em=524 nm). 6-AF488 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC).
    6-AF488 tyramide
  • HY-D2415
    BODIPY-FL staurosporine
    BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery.
    BODIPY-FL staurosporine
Cat. No. Product Name / Synonyms Application Reactivity