Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0512S1

Sulfamerazine-¹³C₆		99.11%
Sulfamerazine-¹³C₆ (RP2632-¹³C₆) is ¹³C labeled Sulfamerazine (HY-B0512). Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein K_D of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection.

HY-151214S

4-Fluorobenzoyl-2,3,5,6-d₄ chloride		98.01%
4-Fluorobenzoyl-2,3,5,6-d₄ chloride is the deuterium labeled 4-Fluorobenzoyl chloride.

HY-165651S

Taurochenodeoxycholic acid-d₄
Taurochenodeoxycholic acid-d4 (TCDCA-d4) is the deuterium labeled Taurochenodeoxycholic acid. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties.

HY-W698472

Hydroxyurea-¹⁵N
Hydroxyurea-¹⁵N (Hydroxycarbamide-¹⁵N) is the ¹⁵N labeled Hydroxyurea (HY-B0313). Hydroxyurea is a cell apoptosis inducer that inhibit DNA synthesis through inhibition of ribonucleotide reductase. Hydroxyurea shows anti-orthopoxvirus activity.

HY-N7092S2

D-Fructose-¹³C-1		98.0%
D-Fructose-¹³C-1 is the ¹³C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.

HY-10163S

Dabigatran-d₄
Dabigatran-d₄ is deuterium labeled Dabigatran. Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC₅₀=10 nM).

HY-109128S

Danicamtiv-d₆
Danicamtiv-d₆ (MYK-491-d₆) is a deuterated labeled Danicamtiv (HY-109128). Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.

HY-B1145S

Chlorhexidine-d₈ dihydrochloride
Chlorhexidine-d₈ (dihydrochloride) is the deuterium labeled Chlorhexidine dihydrochloride (HY-B1145). Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).

HY-W010256S

D-Xylulose-1-¹³C		99.22%
D-Xylulose-1-¹³C is the ¹³C labeled D-Xylulose. D-xylulose is a precursor of the pentiol D-arabi.

HY-B1659S1

Glycerol-¹³C		99.29%
Glycerol-¹³C is the ¹³C labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.

HY-B1617AS

Zuclomiphene-d₄ citrate		99.0%
Zuclomiphene-d₄ citrate is a deuterium labeled Zuclomiphene citrate (HY-B1617A). Zuclomiphene citrate is a cis isomer of Clomiphene citrate (HY-B0463). Zuclomiphene citrate is orally active and has an antiestrogenic effect. Zuclomiphene can reduce cholesterol levels. Zuclomiphene citrate can be for the researches of endocrinology and metabolic disease.

HY-W002300S

Boc-L-Valine-d₈		99.62%
Boc-L-Valine-d₈ is the deuterium labeled Boc-L-Valine.

HY-N1150S2

Thymidine-¹³C		99.11%
Thymidine-¹³C is the ¹³C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication

HY-W777360

Harman-¹³C₂,¹⁵N		99.66%
Harman-¹³C₂,¹⁵N is ¹³C and ¹⁵N labeled Harmane. Harmane is a benzodiazepine receptor inhibitor (IC₅₀=7 μM), with IC₅₀ values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin, with IC₅₀ values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC₅₀=30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF).

HY-W015301S2

Dimethyl adipate-d₈		98.0%
Dimethyl adipate-d₈ (Hexanedioic acid dimethyl ester-d₈) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.

HY-B0579S3

Cyclosporin A-¹³C₂,d₄
Cyclosporin A-¹³C₂,d₄ (Cyclosporine A-¹³C₂,d₄; Ciclosporin A-¹³C₂,d₄) is a ¹³C labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.

HY-B0925S

Oxacillin-¹³C₆ sodium		99%
Oxacillin-¹³C₆ (sodium) is the ¹³C₆ labeled Oxacillin (sodium). Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.

HY-N0108S

Physcion-d₃		99.82%
Physcion-d₃ (Parietin-d₃) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC₅₀ and a K_d of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.

HY-Y1359S

2-Methylimidazole-d₆
2-Methylimidazole-d₆ is the deuterium labeled 2-Methylimidazole.

HY-145008S

(±)9(10)-DiHOME-d₄		99.9%
(±)9(10)-DiHOME-d₄ is the deuterium labeled (±)9(10)-DiHOME.

Name
Email *

	Sorry, but the email address you supplied was invalid.