2. Others Anti-infection
  3. Isotope-Labeled Compounds Bacterial
  4. Physcion-d3

Physcion-d3  (Synonyms: Parietin-d3; Rheochrysidin-d3)

Cat. No.: HY-N0108S Purity: 99.82%
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Physcion-d3 (Parietin-d3) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.

For research use only. We do not sell to patients.

Physcion-d<sub>3</sub> Chemical Structure

Physcion-d3 Chemical Structure

CAS No. : 1215751-27-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Physcion-d3:

Physcion-d3 Related Antibodies

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Description

Physcion-d3 (Parietin-d3) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Physcion-d3 Related Antibodies
Molecular Weight

287.28

Formula

C16H9D3O5
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=CC(OC([2H])([2H])[2H])=CC(O)=C2C(C3=C(O)C=C(C)C=C31)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.67 mg/mL (23.22 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4809 mL 17.4046 mL 34.8092 mL
5 mM 0.6962 mL 3.4809 mL 6.9618 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4809 mL 17.4046 mL 34.8092 mL 87.0231 mL
5 mM 0.6962 mL 3.4809 mL 6.9618 mL 17.4046 mL
10 mM 0.3481 mL 1.7405 mL 3.4809 mL 8.7023 mL
15 mM 0.2321 mL 1.1603 mL 2.3206 mL 5.8015 mL
20 mM 0.1740 mL 0.8702 mL 1.7405 mL 4.3512 mL
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Physcion-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Physcion-d31215751-27-1Parietin-d3 Rheochrysidin-d3Isotope-Labeled CompoundsBacterialInhibitorinhibitorinhibit

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