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  2. Physcion

Physcion (Synonyms: Parietin; Rheochrysidin)

Cat. No.: HY-N0108 Purity: >98.0%
Handling Instructions

Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.

For research use only. We do not sell to patients.

Physcion Chemical Structure

Physcion Chemical Structure

CAS No. : 521-61-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg USD 190 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively[1][2]. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects[2].

IC50 & Target

IC50: 38.5 μM (6-phosphogluconate dehydrogenase)[1]
Kd: 26.0 μM (6-phosphogluconate dehydrogenase)[1]

Storage

4°C, protect from light

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (17.59 mM; Need ultrasonic and warming)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5179 mL 17.5895 mL 35.1791 mL
5 mM 0.7036 mL 3.5179 mL 7.0358 mL
10 mM 0.3518 mL 1.7590 mL 3.5179 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

284.26

Formula

C₁₆H₁₂O₅

CAS No.

521-61-9

SMILES

O=C1C2=C(C=C(C)C=C2O)C(C3=CC(OC)=CC(O)=C13)=O

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Physcion
Cat. No.:
HY-N0108
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Physcion

Cat. No.: HY-N0108