Acid Yellow 36  (Synonyms: Metanil Yellow)

Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes^[1][2][3].

Acid Yellow 36 acts as an inducer of a specific form of microsomal P-450 and cytosolic glutathione-S-transferase (GST) and quinone reductase (QR), which may involve a cytosolic Ah receptor^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

375.38

C₁₈H₁₄N₃NaO₃S

587-98-4

Solid

Brown to orange

O=S(C1=CC=CC(/N=N/C2=CC=C(NC3=CC=CC=C3)C=C2)=C1)(O[Na])=O

Room temperature in continental US; may vary elsewhere.

RT, protect from light

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Sharma UK, et al. Ameliorating efficacy of eugenol against metanil yellow induced toxicity in albino Wistar rats. Food Chem Toxicol. 2019;126:34-40.  [Content Brief]

  [2]. Nakano N, et al. Development of a monitoring system for vinyl chloride gas in air by using an HCl monitoring tape and pyrolyzer. Talanta. 1996;43(3):459-463.  [Content Brief]

  [3]. Ramchandani S, et al. Effect of oral and parenteral administration of metanil yellow on some hepatic and intestinal biochemical parameters. J Appl Toxicol. 1997;17(1):85-91.  [Content Brief]