Anti-Mouse VEGF-A Antibody (2G11-2A05) 

Anti-Mouse VEGF-A Antibody (2G11-2A05) is a rat-derived IgG2a κ type antibody inhibitor, tragrting to mouse VEGF-A with high affinity. Anti-Mouse VEGF-A Antibody (2G11-2A05) shows good anti-tumor effect in gastric cancer xenograft models^[1].

Rat IgG2a kappa

Rat IgG2a kappa, Isotype Control

Mouse

VEGF-A

Anti-Mouse VEGF-A Antibody (2G11-2A05) (5 mg/kg, i.p., twice a week for 2 weeks) exhibits anti tumor effect in gastric cancer xenograft mice models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

22339  [NCBI]

Q00731-3

in vivo VEGF-A neutralization; Western blot

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

Liquid

Colorless to light yellow

[Anti-Mouse VEGF-A Antibody (2G11-2A05)]

Please refer to the lot-specific COA for specific buffer information.

Please store the product under the recommended conditions in the Certificate of Analysis.

• 
  Immobilized HY-P7312 VEGF164 Protein, Mouse can bind Anti-Mouse VEGF-A Antibody (2G11-2A05). The EC₅₀ for this effect is 1.191 μg/mL.

• [1]. Mashima T, et al. Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo. Sci Rep 11, 15125 (2021).