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  5. Rat Anti-Mouse CD86 Antibody (FITC)(YA3447)

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447)

Cat. No.: HY-P83710M
COA
SDS
User Guide for Antibodies Technical Support

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) is a rat-derived and fluorescein isothiocyanate (FITC) IgG2a monoclonal antibody, targeting to CD86.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈 가격 재고 수량
50 T 해외재고보유
100 T 해외재고보유
250 μL   견적 받기  
or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 제품 설명

제품 설명

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) is a rat-derived and fluorescein isothiocyanate (FITC) IgG2a monoclonal antibody, targeting to CD86.
Host

Rat
Clonality

Monoclonal
분자량
Predicted band size: 38 kDa;
Observed band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Mouse
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from Mouse CD86.
Application &
Dilution Ratio
Application Dilution Ratio
FC
FC: Flow Cytometry
5μL per test for million cells or whole blood in 100 μL volume.
Purity Affinity Conjugation FITC
Modification Unmodified Isotype IgG2a
Appearance

Liquid
Formulation

Supplied in PBS with 0.05% Proclin300, 1% BSA.
Storage & Stability

Stored at 2-8°C for 1 year, protect from light, do not freeze.
선적

Shipping with blue ice.
Background
Function：Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (PubMed:23241883)
Subcellular Localization：Cell membrane; Single-pass type I membrane protein
Expression：
Tissue_specificity:Expressed on activated B-cells
Isoforms & Post-Translational Modification：P42082 has 2 isomers: P42082-1: 34666 Da (predicted); P42082-2: 33962 Da (predicted).
Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation
Subunit：Homodimer. Interacts with MARCH8 (By similarity). Interacts (via cytoplasmic domain) with PHB1 and PHB2; the interactions increases after priming with CD40 (PubMed:23241883).
RRID
Database

Entrez Gene: 12524 Mouse

SwissProt: P42082 Mouse

Synonyms
T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1
각종 서류
SDS (252 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Rat Anti-Mouse CD86 Antibody (FITC)(YA3447)
Cat. No.:
HY-P83710M
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