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  4. Antitrypanosomal agent 17

Antitrypanosomal agent 17 (Compd 7a) possesses antiamastigote activity, with an IC50 of 0.03 μM against T. congolense strain IL3000.

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Antitrypanosomal agent 17

Antitrypanosomal agent 17 構造式

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Antitrypanosomal agent 17 関連抗体

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すべてのアイソフォームを表示
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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製品説明

Antitrypanosomal agent 17 (Compd 7a) possesses antiamastigote activity, with an IC50 of 0.03 μM against T. congolense strain IL3000[1].

Cellular Effect
Cell Line Type Value Description References
THP-1 IC50
>100 3
Compound: 7a
Cytotoxicity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin staining based analysis
Cytotoxicity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin staining based analysis
[PMID: 37859713]
THP-1 IC50
> 100 3
Compound: 7a
Cytotoxicity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin staining based analysis
Cytotoxicity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin staining based analysis
[PMID: 37859713]
Vero IC50
>100 3
Compound: 7a
Cytotoxicity against African green monkey Vero cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based analysis
Cytotoxicity against African green monkey Vero cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based analysis
[PMID: 37859713]
Vero IC50
> 100 3
Compound: 7a
Cytotoxicity against African green monkey Vero cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based analysis
Cytotoxicity against African green monkey Vero cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based analysis
[PMID: 37859713]
分子量

349.34

分子式

C19H15N3O4
SMILES

O=[N+]([O-])C(O1)=CC=C1/C=N/N=C/C2=CC=C(OCC3=CC=CC=C3)C=C2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
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Antitrypanosomal agent 17 Related Classifications

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一般には略語で表示されます：C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitrypanosomal agent 17Antitrypanosomal agent17Antitrypanosomal agent-17Parasitetrypanocidal,Inhibitorinhibitorinhibit

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製品名:
Antitrypanosomal agent 17
製品番号:
HY-155400
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