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  3. Argipressin acetate

Argipressin acetate  (Synonyms: Arg8-vasopressin acetate; AVP acetate)

製品番号: HY-W539944 純度: 99.16%
COA 取扱説明書 Technical Support

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.

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CAS 番号 : 129979-57-3

容量 価格(税別) 在庫状況 数量
1 mg $66 在庫あり
5 mg $119 在庫あり
10 mg $158 在庫あり
25 mg $211 在庫あり
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カスタマーレビュー

Based on 10 publication(s) in Google Scholar

Other Forms of Argipressin acetate:

Top Publications Citing Use of Products

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    H9c2 cell viability measured 48 h after exposure to different arginine Argipressin (AVP) concentrations (0–500 µM).

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Representative images of Argipressin (AVP) (300 µM) TUNEL staining.

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Argipressin (AVP) (300 µM). Representative Western blot images.

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Argipressin (AVP) (300 µM). Representative fluorescence images of DCFH-DA loading and quantitative analysis of reactive oxygen species (ROS) levels in H9c2 cells of the Con and AVP groups.

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Argipressin (AVP) (300 µM). Representative immunofluorescence images of nuclear factor E2-associated factor 2 (Nrf2) expression in two groups of cells.

    Vasopressin Receptor アイソフォーム固有の製品をすべて表示:

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    製品説明

    Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4].

    体外実験

    Argipressin (Arg8-vasopressin) (acetate) induces proliferation and prevented cytokine-induced apoptosis in rodent and human beta-cells[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Cell Proliferation Assay[1]

    Cell Line: clonal BRIN BD11 and 1.1B4 cells
    Concentration: 10-6 M
    Incubation Time: 2 h
    Result: Increased proliferation of rodent and human beta-cells.

    Apoptosis Analysis[1]

    Cell Line: clonal BRIN BD11 and 1.1B4 cells
    Concentration: 10-6 M
    Incubation Time: 2 h
    Result: Protected against cytokine-induced beta-cell apoptosis.
    体内実験

    Argipressin (Arg8-vasopressin) (acetate) (25 nmol/kg bw; intraperitoneal injection; once) significantly reduces overall AUC glucose values, but not increases insulin levels in mice[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: NIH Swiss mice (adult; male; 12-14weeks)[1]
    Dosage: 25 nmol/kg bw
    Administration: AVP (25 nmol/kg bw; intraperitoneal injection; once)
    Result: Reduced (P<0.001) overall AUC glucose values,but not increased insulin levels in mice.
    分子量

    1084.23 (free base)

    分子式

    C46H65N15O12S2·xC2H4O2

    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    Sequence

    Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6)

    Sequence Shortening

    CYFQNCPRG-NH2 (Disulfide bridge: Cys1-Cys6)

    輸送条件

    Room temperature in continental US; may vary elsewhere.

    保管条件
    Sealed storage, away from moisture
    Powder -80°C 2 years
      -20°C 1 year
    In solvent -80°C 6 months
      -20°C 1 month
    溶剤 & 溶解度
    体外: 

    H2O : ≥ 100 mg/mL

    *"≥" means soluble, but saturation unknown.

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    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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    参考文献
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    • Molarity Calculator

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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます:C1V1 = C2V2

    濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    製品名:
    Argipressin acetate
    製品番号:
    HY-W539944
    数量:
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