2. Apoptosis GPCR/G Protein
  3. Apoptosis Vasopressin Receptor
  4. Argipressin diacetate

Argipressin diacetate  (Synonyms: Arg8-vasopressin diacetate; AVP diacetate; ADH)

Cat. No.: HY-P0049A
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Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes.

For research use only. We do not sell to patients.

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Argipressin diacetate Chemical Structure

Argipressin diacetate Chemical Structure

CAS No. : 75499-44-4

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Argipressin diacetate Related Antibodies

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Description

Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes[1].

In Vitro

Argipressin (diacetate) (AVP (diacetate)) induces proliferation and prevented cytokine-induced apoptosis in rodent and human beta-cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Argipressin diacetate Related Antibodies

Cell Proliferation Assay[1]

Cell Line: clonal BRIN BD11 and 1.1B4 cells
Concentration: 10-6 M
Incubation Time: 2 h
Result: Increased proliferation of rodent and human beta-cells.

Apoptosis Analysis[1]

Cell Line: clonal BRIN BD11 and 1.1B4 cells
Concentration: 10-6 M
Incubation Time: 2 h
Result: Protected against cytokine-induced beta-cell apoptosis.
In Vivo

Argipressin (diacetate) (AVP (diacetate)) (25 nmol/kg bw; intraperitoneal injection; once) significantly reduces overall AUC glucose values，but not increases insulin levels in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: NIH Swiss mice (adult; male; 12-14weeks) [1]
Dosage: 25 nmol/kg bw
Administration: AVP (25 nmol/kg bw; intraperitoneal injection; once)
Result: Reduced (P<0.001) overall AUC glucose values，but not increased insulin levels in mice.
Clinical Trial
Molecular Weight

1204.34

Formula

C50H73N15O16S2
CAS No.
Sequence Shortening

CYFQNCPRG-NH2 (Disulfide bridge: Cys1-Cys6)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Argipressin diacetate Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Argipressin diacetate75499-44-4Arg8-vasopressin diacetateAVP diacetate ADHApoptosisVasopressin ReceptorArginine vasopressinAVPADHfluid balanceosmolalityInhibitorinhibitorinhibit

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