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  3. Vasopressin Receptor Apoptosis
  4. Argipressin acetate

Argipressin acetate  (Synonyms: Arg8-vasopressin acetate; AVP acetate)

Cat. No.: HY-W539944 Purity: 99.16%
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Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.

For research use only. We do not sell to patients.

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CAS No. : 129979-57-3

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Customer Review

Based on 10 publication(s) in Google Scholar

Other Forms of Argipressin acetate:

Argipressin acetate Related Antibodies

Top Publications Citing Use of Products

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    H9c2 cell viability measured 48 h after exposure to different arginine Argipressin (AVP) concentrations (0–500 µM).

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Representative images of Argipressin (AVP) (300 µM) TUNEL staining.

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Argipressin (AVP) (300 µM). Representative Western blot images.

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Argipressin (AVP) (300 µM). Representative fluorescence images of DCFH-DA loading and quantitative analysis of reactive oxygen species (ROS) levels in H9c2 cells of the Con and AVP groups.

    Argipressin acetate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2022 Dec:206:115265.  [Abstract]

    Argipressin (AVP) (300 µM). Representative immunofluorescence images of nuclear factor E2-associated factor 2 (Nrf2) expression in two groups of cells.

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    V1a Receptor  V1b Receptor  V2 Receptor 

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    • Purity & Documentation

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    Description

    Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4].

    In Vitro

    Argipressin (Arg8-vasopressin) (acetate) induces proliferation and prevented cytokine-induced apoptosis in rodent and human beta-cells[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Argipressin acetate Related Antibodies

    Cell Proliferation Assay[1]

    Cell Line: clonal BRIN BD11 and 1.1B4 cells
    Concentration: 10-6 M
    Incubation Time: 2 h
    Result: Increased proliferation of rodent and human beta-cells.

    Apoptosis Analysis[1]

    Cell Line: clonal BRIN BD11 and 1.1B4 cells
    Concentration: 10-6 M
    Incubation Time: 2 h
    Result: Protected against cytokine-induced beta-cell apoptosis.
    In Vivo

    Argipressin (Arg8-vasopressin) (acetate) (25 nmol/kg bw; intraperitoneal injection; once) significantly reduces overall AUC glucose values, but not increases insulin levels in mice[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: NIH Swiss mice (adult; male; 12-14weeks)[1]
    Dosage: 25 nmol/kg bw
    Administration: AVP (25 nmol/kg bw; intraperitoneal injection; once)
    Result: Reduced (P<0.001) overall AUC glucose values，but not increased insulin levels in mice.
    Molecular Weight

    1084.23 (free base)

    Formula

    C46H65N15O12S2·xC2H4O2
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    Sequence

    Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
    Sequence Shortening

    CYFQNCPRG-NH2 (Disulfide bridge: Cys1-Cys6)
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Sealed storage, away from moisture

    Powder -80°C 2 years
    -20°C 1 year

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    H2O : ≥ 100 mg/mL

    *"≥" means soluble, but saturation unknown.

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation
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    Argipressin acetate Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Argipressin129979-57-3Arg8-vasopressinAVPVasopressin ReceptorApoptosisArginine vasopressinADHfluid balanceosmolalityInhibitorinhibitorinhibit

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