2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. BI 01383298

BI 01383298 is a potent inhibitor of the sodium-citrate co-transporter (SLC13A5) that is highly expressed in the liver.

For research use only. We do not sell to patients.

BI 01383298 Chemical Structure

BI 01383298 Chemical Structure

CAS No. : 2227549-00-8

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 83 In-stock
Solution
10 mM * 1 mL in DMSO USD 83 In-stock
Solid
5 mg USD 75 In-stock
10 mg USD 135 In-stock
25 mg USD 290 In-stock
50 mg USD 470 In-stock
100 mg USD 750 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

BI 01383298 is a potent inhibitor of the sodium-citrate co-transporter (SLC13A5) that is highly expressed in the liver[1].

IC50 & Target

SLC13A5[1]
Molecular Weight

445.34

Formula

C19H19Cl2FN2O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1CCN(S(=O)(C2=CC(Cl)=CC(Cl)=C2)=O)CC1)NCC3=CC=C(F)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 37.5 mg/mL (84.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2455 mL 11.2274 mL 22.4548 mL
5 mM 0.4491 mL 2.2455 mL 4.4910 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2455 mL 11.2274 mL 22.4548 mL 56.1369 mL
5 mM 0.4491 mL 2.2455 mL 4.4910 mL 11.2274 mL
10 mM 0.2245 mL 1.1227 mL 2.2455 mL 5.6137 mL
15 mM 0.1497 mL 0.7485 mL 1.4970 mL 3.7425 mL
20 mM 0.1123 mL 0.5614 mL 1.1227 mL 2.8068 mL
25 mM 0.0898 mL 0.4491 mL 0.8982 mL 2.2455 mL
30 mM 0.0748 mL 0.3742 mL 0.7485 mL 1.8712 mL
40 mM 0.0561 mL 0.2807 mL 0.5614 mL 1.4034 mL
50 mM 0.0449 mL 0.2245 mL 0.4491 mL 1.1227 mL
60 mM 0.0374 mL 0.1871 mL 0.3742 mL 0.9356 mL
80 mM 0.0281 mL 0.1403 mL 0.2807 mL 0.7017 mL
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BI 01383298 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BI 013832982227549-00-8BI01383298BI-01383298Sodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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