2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Carbazochrome

Carbazochrome is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome is an antihemorrhagic agent.

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Carbazochrome

Carbazochrome 構造式

CAS 番号 : 69-81-8

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 33 在庫あり
Solution
10 mM * 1 mL in Water USD 33 在庫あり
Solid
100 mg $30 在庫あり
250 mg $50 在庫あり
500 mg   お問い合わせ  
1 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Carbazochrome 関連抗体

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Adrenergic Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
α adrenergic receptor β adrenergic receptor

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  • 純度とドキュメンテーション

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製品説明

Carbazochrome is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome is an antihemorrhagic agent[1].

体外実験

Carbazochrome (0.1-10 μM) inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3 in a concentration-dependent manner[1]. Carbazochrome (0.1-1 μM), when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Carbazochrome 関連抗体
体内実験

Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats weighing 180-230 g[2]
Dosage: 10 mg/kg
Administration: I.v.; injected 30, 60, or 90 min before Ioxaglate injection (4 g I/kg, i.v.).
Result: Attenuated the Ioxaglate-increased vascular permeability at the dose of 1, 5 and 10 mg/kg in a dose-dependent manner, achieving statistical significance at 5 and 10 mg/kg.
分子量

236.23

分子式

C10H12N4O3
CAS 番号
Appearance

Solid

Color

Brown to reddish brown

SMILES

O=C1/C(C=C2C(O)CN(C)C2=C1)=N\NC(N)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 5 mg/mL (21.17 mM; ultrasonic and adjust pH to 12 with NaOH)

DMSO : 4 mg/mL (16.93 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2332 mL 21.1658 mL 42.3316 mL
5 mM 0.8466 mL 4.2332 mL 8.4663 mL
10 mM 0.4233 mL 2.1166 mL 4.2332 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

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体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.2332 mL 21.1658 mL 42.3316 mL 105.8291 mL
5 mM 0.8466 mL 4.2332 mL 8.4663 mL 21.1658 mL
10 mM 0.4233 mL 2.1166 mL 4.2332 mL 10.5829 mL
15 mM 0.2822 mL 1.4111 mL 2.8221 mL 7.0553 mL
H2O 20 mM 0.2117 mL 1.0583 mL 2.1166 mL 5.2915 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Carbazochrome Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Carbazochrome69-81-8Adrenergic ReceptorBeta ReceptorcapillarystabiliserhaemorrhageantihemorrhagicInhibitorinhibitorinhibit

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製品名:
Carbazochrome
製品番号:
HY-B1587
数量:
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