CD24/Siglec-10 blocking peptide, CSBP

Cat. No.: HY-P10091 Pureté: 98.91%: Fiche technique
COA

SDS
Instruction de manipulation
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CD24/Siglec-10 blocking peptide, CSBP can not only block the interaction of CD24/Siglec-10 but also PD-1/PD-L1. CD24/Siglec-10 blocking peptide, CSBP can induce the phagocytosis of tumor cell.

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Synthèse de peptides personnalisée

CD24/Siglec-10 blocking peptide, CSBP Chemical Structure

Size	Stock	Quantité
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtenir un devis
100 mg	Obtenir un devis

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* Veuillez sélectionner la quantité avant d'ajouter des articles.

This product is a controlled substance and not for sale in your territory.

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Based on 1 Customer Validation

Recommandations en vedette

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Activité biologique
Pureté et documentation
Références
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Description

CD24/Siglec-10 blocking peptide, CSBP can not only block the interaction of CD24/Siglec-10 but also PD-1/PD-L1. CD24/Siglec-10 blocking peptide, CSBP can induce the phagocytosis of tumor cell^[1].

Masse moléculaire

985.09

Formule

C₄₇H₆₈N₈O₁₅

Appearance

Solid

Color

White to off-white

Sequence

{d-Leu}-{d-Asp}-{d-Val}-{d-Phe}-{d-Leu}-{d-Tyr}-{d-Ser}-{d-Glu}

Sequence Shortening

{d-Leu}-{d-Asp}-{d-Val}-{d-Phe}-{d-Leu}-{d-Tyr}-{d-Ser}-{d-Glu}

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvant et solubilité

In Vitro:

DMSO : 10 mg/mL (10.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0151 mL	5.0757 mL	10.1514 mL
5 mM	0.2030 mL	1.0151 mL	2.0303 mL
10 mM	0.1015 mL	0.5076 mL	1.0151 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureté et documentation

Purity: 98.91%

Select Batch:

Fiche technique (272 KB) SDS (252 KB)

COA (248 KB) LCMS (101 KB) Elemental Analysis Report (108 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Wenhui Shen, et al. Discovery of a novel dual-targeting D-peptide to block CD24/Siglec-10 and PD-1/PD-L1 interaction and synergize with radiotherapy for cancer immunotherapy. J Immunother Cancer. 2023 Jun;11(6):e007068. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0151 mL	5.0757 mL	10.1514 mL	25.3784 mL
	5 mM	0.2030 mL	1.0151 mL	2.0303 mL	5.0757 mL
	10 mM	0.1015 mL	0.5076 mL	1.0151 mL	2.5378 mL