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  3. Fluorescent Dye
  4. H-D-Phe-Pip-Arg-pNA

H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (H-D-Phe-Pip-Arg-pNA hydrochloride and H-D-Phe-Pip-Arg-pNA acetate) usually boasts enhanced water solubility and stability.

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Síntesis de péptidos personalizados

H-D-Phe-Pip-Arg-pNA

H-D-Phe-Pip-Arg-pNA Estructura química

No. CAS : 64815-81-2

Tamaño Precio Stock
5 mg Pide un presupuesto y un plazo de entrega
10 mg Pide un presupuesto y un plazo de entrega

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H-D-Phe-Pip-Arg-pNA Related Antibodies

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Descripciòn

H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform[1][2].

Peso molecular

552.63

Fòrmula

C27H36N8O5
No. CAS
Sequence Shortening

{D-Phe}-{Pip}-R-pNA
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvente y solubilidad
In Vitro: 

DMSO : 25 mg/mL (45.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8095 mL 9.0476 mL 18.0953 mL
5 mM 0.3619 mL 1.8095 mL 3.6191 mL
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8095 mL 9.0476 mL 18.0953 mL 45.2382 mL
5 mM 0.3619 mL 1.8095 mL 3.6191 mL 9.0476 mL
10 mM 0.1810 mL 0.9048 mL 1.8095 mL 4.5238 mL
15 mM 0.1206 mL 0.6032 mL 1.2064 mL 3.0159 mL
20 mM 0.0905 mL 0.4524 mL 0.9048 mL 2.2619 mL
25 mM 0.0724 mL 0.3619 mL 0.7238 mL 1.8095 mL
30 mM 0.0603 mL 0.3016 mL 0.6032 mL 1.5079 mL
40 mM 0.0452 mL 0.2262 mL 0.4524 mL 1.1310 mL
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H-D-Phe-Pip-Arg-pNA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H-D-Phe-Pip-Arg-pNA64815-81-2S-2238S2238S 2238Fluorescent Dyechromogenicsubstratefibrinogenthrombinantithrombin-heparincofactorAT-IIIInhibitorinhibitorinhibit

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Nombre del producto:
H-D-Phe-Pip-Arg-pNA
Cat. No.:
HY-123275
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