Search Result
Results for "
chromogenic
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-P4202
-
Suc-AEPF-pNA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
-
- HY-W039892
-
pNPG_1
|
Others
|
Others
|
4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-nitrophenol 4-Nitrophenyl β-D-glucuronide is a chromogenic compound and is the chromogenic substrate for β-glucuronidase .
|
-
-
- HY-W357151
-
|
Fluorescent Dye
|
Others
|
6-Chloro-3-indoxyl-α-D-mannopyranoside is a chromogenic substrate for α-mannosidase resulting in a salmon colored precipitate upon cleavage.
|
-
-
- HY-W320032
-
|
Fluorescent Dye
|
Others
|
5-Bromo-1H-indol-3-yl octanoate is a chromogenic substrate for esterase with C8 activity. 5-Bromo-1H-indol-3-yl octanoate yields a blue precipitate when cleaved.
|
-
-
- HY-W345102
-
-
-
- HY-P4202A
-
Suc-AEPF-pNA TFA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
-
- HY-W116594
-
|
Fluorescent Dye
|
Infection
|
X-GalNAc is a chromogenic substrate for for N-acetyl-β-galactosidase, used to determine the presence or absence of a cloned DNA insert in bacteria growing on agar plates .
|
-
-
- HY-114522
-
-
-
- HY-W141825
-
|
Fluorescent Dye
|
Infection
Metabolic Disease
|
N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .
|
-
-
- HY-P10083
-
-
-
- HY-P10094
-
|
Fluorescent Dye
|
Others
|
β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
|
-
-
- HY-P4458
-
|
Ser/Thr Protease
|
Cancer
|
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
|
-
-
- HY-P3949
-
|
Fluorescent Dye
|
Others
|
Fluorescent Substrate for Glu-Specific Proteases is a V8 protease-Specific chromogenic substrate .
|
-
-
- HY-P4518
-
|
Ser/Thr Protease
|
Others
|
Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
|
-
-
- HY-D0908
-
|
Fluorescent Dye
|
Others
|
Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins.
|
-
-
- HY-W337201
-
|
Fluorescent Dye
|
Others
|
5-Bromo-4-chloro-3-indolyl β-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases .
|
-
-
- HY-P4475
-
-
-
- HY-P4460
-
|
Ser/Thr Protease
|
Cancer
|
AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
|
-
-
- HY-P4482
-
|
Bacterial
|
Infection
|
Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
|
-
-
- HY-P4464
-
|
Ser/Thr Protease
|
Cancer
|
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
|
-
-
- HY-P4470
-
|
Ser/Thr Protease
|
Cancer
|
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
|
-
-
- HY-P3934
-
|
HIV Protease
|
Infection
|
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .
|
-
-
- HY-W133997
-
|
Fluorescent Dye
|
Others
|
Chromotrope 2R can be used as a chromogenic analytical probe for the quantification of proteins. Basic proteins stained red and the peak wavelength red shifts from 501.6 nm to 567 nm .
|
-
-
- HY-15907
-
NSC240867; Benzylamino-NBD
|
Fluorescent Dye
|
Others
|
BBD (NSC240867) is a biochemical reagent/chromogenic reagent.
|
-
-
- HY-114958
-
|
Fluorescent Dye
|
Others
|
RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase .
|
-
-
- HY-15903
-
-
-
- HY-15905
-
N-Ethyl-N-sulfopropylaniline sodium salt
|
Fluorescent Dye
|
Others
|
ALPS(N-Ethyl-N-sulfopropylaniline sodium salt) is a bio-chemical reagents/chromogenic reagent.
|
-
-
- HY-P0021A
-
Spectrozyme PCa; Chromozym Pca diacetate
|
Fluorescent Dye
|
Others
|
D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
|
-
-
- HY-137816
-
|
Others
|
Others
|
6-Chloro-3-indolyl-β-D-glucuronide cyclohexylammonium salt is a chromogenic substrate for β-glucuronidase. 6-Chloro-3-indolyl-β-D-glucuronide cyclohexylammonium salt produces a salmon colored precipitate upon cleavage .
|
-
-
- HY-15928
-
Para-nitrophenyl phosphate disodium
|
Fluorescent Dye
|
Others
|
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.
|
-
-
- HY-112276
-
|
Fluorescent Dye
|
Others
|
Beryllon II is a widely used chromogenic reagent that is used to determine many elements, such as Mo, Mg and Co, and also used for the determination of proteins.
|
-
-
- HY-15909
-
BCIP p-toluidine salt; X-phosphate p-toluidine salt
|
Fluorescent Dye
|
Others
|
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.
|
-
-
- HY-52112
-
5-bromo-4-chloroindoxyl acetate
|
Fluorescent Dye
|
Others
|
BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase .
|
-
-
- HY-137276
-
Bluo-Gal
|
Fluorescent Dye
|
Others
|
5-Bromo-3-indolyl β-D-galactopyranoside (Bluo-Gal) is a chromogenic substrate to detect bacterial β-D-galactosidase activity. 5-Bromo-3-indolyl β-D-galactopyranoside is used both to recognize labelled myofibers, and beta-gal positive organelles inside single myofibers .
|
-
-
- HY-15930C
-
BM blue monosulfate; Sure Blue TMB monosulfate
|
Fluorescent Dye
|
Others
|
TMB monosulfate is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualizing reagent used in enzyme-linked immunosorbent assays (ELISA).
|
-
-
- HY-15930
-
BM blue; Sure Blue TMB
|
Fluorescent Dye
|
Others
|
TMB (BM blue) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).
|
-
-
- HY-15930A
-
BM blue dihydrochloride; Sure Blue TMB dihydrochloride
|
Fluorescent Dye
|
Others
|
TMB dihydrochloride (BM blue dihydrochloride) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).
|
-
-
- HY-D1676
-
|
Phosphatase
|
Others
|
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
|
-
-
- HY-15914
-
DCHBS
|
Fluorescent Dye
|
Others
|
DHBS is Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions.
|
-
-
- HY-W455884
-
|
Others
|
Others
|
3,5-Dichloro-2-hydroxybenzenesulfonic acid is used in conjunction with Ampyrone (HY-B1398) (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantification of peroxidase in coupled enzymatic reactions. 3,5-Dichloro-2-hydroxybenzenesulfonic acid is used to measure hydrogen peroxide production in conjunction with peroxidase .
|
-
-
- HY-P4039
-
|
HCV Protease
|
Infection
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
-
-
- HY-W411361
-
PCNPH
|
Fluorescent Dye
|
Cancer
|
Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone (PCNPH) is a chromogenic substrate to peroxidase enzymes. Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone can form a purple indamine dye with peroxidase enzymes and peroxides .
|
-
-
- HY-123275A
-
S-2238 hydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
|
-
-
- HY-123275
-
S-2238
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
|
-
-
- HY-123275C
-
S-2238 dihydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
|
-
-
- HY-123275B
-
S-2238 acetate
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
|
-
-
- HY-15934
-
X-GAL
1 Publications Verification
BCIG
|
Fluorescent Dye
Glucosidase
|
Others
|
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
|
-
-
- HY-P0022
-
-
-
- HY-P0022A
-
-
-
- HY-D1213
-
Dipotassium nitrocatechol sulfate
|
Biochemical Assay Reagents
|
Others
|
4-Nitrocatechol sulfate dipotassium salt (Dipotassium nitrocatechol sulfate) is a chromogenic substrate for sulphatase .
|
-
- HY-P3936
-
|
Fluorescent Dye
|
Others
|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
|
-
- HY-P3126
-
|
Factor Xa
|
Others
|
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
|
-
- HY-W154295
-
|
Fluorescent Dye
|
Others
|
Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity .
|
-
- HY-153829
-
-
- HY-P0020
-
tos-GPR-ANBA-IPA
|
Biochemical Assay Reagents
|
Others
|
Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA can be used for luminescence measurement .
|
-
- HY-15923
-
|
Reactive Oxygen Species
|
Others
|
MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium .
|
-
- HY-15932
-
TOOS sodium salt
|
Biochemical Assay Reagents
|
Others
|
TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .
|
-
- HY-W016188
-
|
Cholinesterase (ChE)
|
Others
|
1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .
|
-
- HY-P4453
-
|
Caspase
|
Cancer
|
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
|
-
- HY-P0020A
-
tos-GPR-ANBA-IPA acetate
|
|
|
Tos-Gly-Pro-Arg-ANBA-IPA (tos-GPR-ANBA-IPA) acetate is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA acetate can be used for luminescence measurement .
|
-
- HY-119244
-
|
Dipeptidyl Peptidase
|
Others
|
Gly-Pro-pNA hydrochloride is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA can be used to screen for DPP IV inhibitors .
|
-
- HY-W011411
-
|
Glucosidase
|
Others
|
4-Nitrophenyl a-D-glucopyranoside is a chromogenic substrate for α-glucosidase. 4-Nitrophenyl a-D-glucopyranoside can be used to measure of α-glucosidase activity .
|
-
- HY-15927
-
|
Biochemical Assay Reagents
|
Others
|
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside can be used to measure of β-glucosidase activity .
|
-
- HY-W039938
-
|
Fluorescent Dye
|
Others
|
4-Nitrophenyl β-D-xylopyranoside is a chromogenic β-xylosidase substrate. 4-Nitrophenyl β-D-xylopyranoside can be used to test β-xylosidase activity .
|
-
- HY-P6027A
-
|
Fluorescent Dye
|
Others
|
H-D-CHA-Ala-Arg-pNA (diacetate) is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-150523). H-D-CHA-Ala-Arg-pNA (diacetate) is a chromogenic substrate for the amidolytic assay .
|
-
- HY-118320
-
Mordant orange 1
|
Fluorescent Dye
|
Others
|
Alizarine Yellow R (Mordant orange 1), a salicylic acid derivative, is a azo dye. Alizarine Yellow R is mostly used as a pH indicator, as a biological stain in chemical examinations and also in dyeing industries .
|
-
- HY-125744
-
|
Biochemical Assay Reagents
|
Others
|
Palmitoyl thio-PC is a chromogenic substrate specific for PLA2 with a palmitoyl thioester at the sn-2 position. Palmitoyl thio-PC could be used to measure bee-venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system .
|
-
- HY-113245
-
|
Endogenous Metabolite
|
Others
|
3-Indolyl-β-D-glucuronide, a chromogenic substrate for β-D-glucuronidase, employs in the detection and enumeration of E. coli, yielding a blue precipitate upon cleavage. 3-Indolyl-β-D-glucuronide in? patients' plasma act as a new indicator of renal failure .
|
-
- HY-108913
-
|
Beta-lactamase
Antibiotic
|
Infection
|
Nitrocefin is a chromogenic β-lactamase substrate that undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
|
-
- HY-P3480
-
|
Fluorescent Dye
|
Others
|
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
|
-
- HY-137827
-
p-Nitrophenyl β-D-Cellobioside
|
Fluorescent Dye
|
Others
|
4-Nitrophenyl β-D-Cellobioside (p-Nitrophenyl β-D-cellobioside) is a cellotriose analog, a chromogenic substrate for the detection of cellulase activity. Exoglucanases, endoglucanases, and β-glucosidases hydrolyze 4-Nitrophenyl β-D-Cellobioside to yield p-nitrophenol (PNP) .
|
-
- HY-W247131
-
|
Fluorescent Dye
|
Neurological Disease
|
DASPEI is a cationic styrenyl mitochondrial dye with large Stokes shift. DASPEI has excitation and emission wavelength at 550/573 nm, which has good light chromogenic property. DASPEI can stain mitochondria in living cells with good labeling property. And DASPEI can also be used to stain presynaptic nerve endings independently of neuronal activity .
|
-
- HY-132239
-
5-Bromo-6-chloro-3-indolyl-beta-D-galactoside
|
Others
|
Others
|
5-Bromo-6-chloro-3-indolyl β-D-Galactopyranoside (contains ca. 10% Ethyl Acetate) (5-Bromo-6-chloro-3-indolyl-beta-D-galactoside) is a chromogenic substrate of β-galactosidase (β-gal) .
|
-
- HY-D1266
-
NO-red
|
Fluorescent Dye
|
Others
|
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .
|
-
- HY-123633
-
|
Glucosidase
|
Others
|
4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity . 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively .
|
-
- HY-D1510
-
|
Biochemical Assay Reagents
|
Others
|
4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety .
|
-
- HY-W127380
-
|
Biochemical Assay Reagents
|
Others
|
Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.
|
-
- HY-137779
-
|
Biochemical Assay Reagents
|
Others
|
5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside, a chromogenic substrate for the detection of β-galactosidase activity. It is commonly used in molecular biology techniques such as gene expression analysis and reporter gene analysis. When β-galactosidase cleaves X-Gluc, a blue precipitate is produced, which can be observed by microscopy or other detection methods. X-Gluc has high sensitivity and specificity for the detection of β-galactosidase activity, making it a widely used tool in molecular biology research.
|
-
- HY-117724
-
|
PAI-1
|
Cardiovascular Disease
|
AZ3976 is a potent plasminogen activator inhibitor type 1 (PAI-1) inhibitor with an IC50 value of 26 μM in an enzymatic chromogenic assay. AZ3976 is active with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 does not bind to active PAI-1 but bound reversibly to latent PAI-1. AZ3976 inhibits PAI-1 by enhancing the latency transition of active PAI-1. AZ3976 displays profibrinolytic activities in a human plasma clot lysis assay .
|
-
- HY-14536
-
Basic Blue 9; CI-52015; Methylthioninium chloride
|
Guanylate Cyclase
Monoamine Oxidase
NO Synthase
Microtubule/Tubulin
|
Infection
Neurological Disease
Cancer
|
Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .
|
-
- HY-15902
-
AzBTS-(NH4)2
|
Fluorescent Dye
|
Others
|
ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.
|
-
- HY-15924
-
Thiazolyl Blue
Maximum Cited Publications
99 Publications Verification
MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide
|
Fluorescent Dye
|
Others
|
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .
|
-
- HY-15925
-
NBT
|
Fluorescent Dye
|
Others
|
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .
|
-
- HY-15931
-
TMBZ-PS
|
Fluorescent Dye
|
Others
|
TMB-PS(102062-36-2) is N-(3-sulfopropyl)-3,3',5,5'-tetramenthylbenzidine sodium salt; White - pale yellow crystalline powder, soluble in water, can be used under neutral, acidic and alkaline conditions.
|
-
- HY-15935
-
|
Fluorescent Dye
|
Others
|
X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) .
|
-
- HY-D0711
-
Foxgreen; IC Green; Cardiogreen
|
Fluorescent Dye
|
Others
|
Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
|
-
- HY-16710
-
GPN; Glycylproline p-nitroanilide tosylate
|
Fluorescent Dye
|
Others
|
GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay.
|
-
- HY-D0717
-
Diaminofluorescein-FM diacetate
|
Fluorescent Dye
|
Others
|
DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .
|
-
- HY-P0019
-
-
- HY-P0021
-
Chromozym Pca
|
Fluorescent Dye
|
Others
|
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).
|
-
- HY-B1046
-
-
- HY-P0019A
-
|
Fluorescent Dye
|
Others
|
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
|
-
- HY-12591
-
D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium
|
Fluorescent Dye
|
Others
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-12591A
-
D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
|
Fluorescent Dye
|
Others
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-D0055
-
|
Cytochrome P450
|
Others
|
3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that generates blue fluorescent product upon enzyme cleavage
Target: Cytochrome P450
3-Cyano-7-ethoxycoumarin is a fluorescent probe useful in microsomal dealkylase studies.
|
-
- HY-D0829
-
|
DNA Stain
|
Others
|
3,6-Dichlorotrimellitic anhydride is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
|
-
- HY-D0828
-
|
DNA Stain
|
Others
|
3,6-Dichlorotrimellitic acid is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
|
-
- HY-N0116
-
Natural Black 1; Haematoxylin
|
Amyloid-β
|
Others
|
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
|
-
- HY-D0831
-
|
Fluorescent Dye
|
Others
|
WST-8 is a water-soluble tetrazolium dye, WST-8 enhances sensitivity of the WST-8-based assay over the conventional MTS-based assay.
|
-
- HY-D0516
-
Sudan Blue II; Oil Blue 35
|
Fluorescent Dye
|
Others
|
Solvent Blue 35 (Sudan Blue II; Oil Blue 35) is a dye used for colouring alcoholic and hydrocarbon based solvents. It is used for staining triglycerides in animal tissues.
|
-
- HY-D0006
-
|
Fluorescent Dye
|
Others
|
Bathophenanthroline is an agent used for the measurement of iron concentrations in aqueous , serum and urine samples by colorimetry.
|
-
- HY-12591B
-
D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium
|
Fluorescent Dye
|
Others
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-P1003
-
|
Fluorescent Dye
|
Others
|
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
|
-
- HY-101895
-
FDG
|
Fluorescent Dye
|
Others
|
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm).
|
-
- HY-D0935A
-
MUG
|
Fluorescent Dye
|
Others
|
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
|
-
- HY-D1026
-
3-Carboxyumbelliferyl-β-D-galactopyranoside
|
Fluorescent Dye
|
Others
|
CUG (3-Carboxyumbelliferyl-β-D-galactopyranoside) is a fluorogenic substrate (λex=386, λem=445 nm, ε=32K).
|
-
- HY-D0994
-
4-MUP; MUP
|
Phosphatase
|
Others
|
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .
|
-
- HY-D0995
-
MESG
|
Fluorescent Dye
|
Others
|
7-Methyl-6-thioguanosine (MESG) is a chromophoric substrate which can be used for the quantitation of inorganic phosphate. 7-Methyl-6-thioguanosine is also used to determine the activity of purine nucleoside phosphorylase .
|
-
- HY-111377
-
|
Fluorescent Dye
|
Others
|
Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group .
|
-
- HY-P1448
-
-
- HY-112641A
-
|
Fluorescent Dye
|
Others
|
AkaLumine hydrochloride is a luciferin analogue, with a Km of 2.06 μM for recombinant Fluc protein.
|
-
- HY-111653
-
CycLuc1
1 Publications Verification
|
Reactive Oxygen Species
|
Others
|
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
|
-
- HY-D0144
-
Methoxyresorufin
|
Cytochrome P450
|
Others
|
Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .
|
-
- HY-D0145
-
Resorufin ethyl ether
|
Cytochrome P450
NO Synthase
|
Others
|
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase .
|
-
- HY-19948
-
TRx0237 mesylate; Methylene blue leuco base mesylate
|
Amyloid-β
|
Neurological Disease
|
Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes .
|
-
- HY-129096
-
|
Fluorescent Dye
|
Others
|
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+) .
|
-
- HY-P3363
-
|
Caspase
|
Cancer
|
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
|
-
- HY-146248
-
|
Poly(ADP-ribose) Glycohydrolase (PARG)
|
Others
|
TFMU-ADPr is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr has excellent reactivity, generality, stability, and usability. TFMU-ADPr is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes .
|
-
- HY-D1505
-
|
Fluorescent Dye
|
Others
|
4-(N,N-Dimethylamino)azobenzene-4'-isothiocyanate is a chromophoric, hydrophobic reagent for probing membrane-buried segments of intrinsic proteins .
|
-
- HY-D1582
-
|
Fluorescent Dye
|
Others
|
C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .
|
-
- HY-D1647
-
|
Phospholipase
|
Others
|
7-Hydroxycoumarinyl-γ-linolenate is a cytosolic phospholipase A2 (cPLA2) fluorogenic substrate. 7-Hydroxycoumarinyl-γ-linolenate can be used to monitor the enzymatic activity of cPLA2 .
|
-
- HY-D1634
-
|
Cathepsin
|
Others
|
Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM -1s -1. The high concentration of BZ-FVR-AMC inhibits the substrate .
|
-
- HY-P1093
-
|
Caspase
|
Others
|
Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase .
|
-
- HY-P2614
-
|
Caspase
|
Others
|
Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3 .
|
-
- HY-P2685
-
|
Fluorescent Dye
|
Others
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase .
|
-
- HY-P3098
-
|
MMP
|
Others
|
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .
|
-
- HY-P3120
-
|
MMP
|
Others
|
Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).
|
-
- HY-P2616
-
-
- HY-D0994A
-
4-MUP disodium; MUP disodium
|
Phosphatase
|
Others
|
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .
|
-
- HY-148073
-
-
- HY-D1670
-
-
- HY-D1208
-
-
- HY-W354821
-
4-MUD
|
Fluorescent Dye
|
Metabolic Disease
|
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .
|
-
- HY-W357142
-
-
- HY-W010991
-
-
Cat. No. |
Product Name |
Type |
-
- HY-P4202
-
Suc-AEPF-pNA
|
Chromogenic Substrates
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-W357151
-
|
Chromogenic Substrates
|
6-Chloro-3-indoxyl-α-D-mannopyranoside is a chromogenic substrate for α-mannosidase resulting in a salmon colored precipitate upon cleavage.
|
-
- HY-W320032
-
|
Chromogenic Substrates
|
5-Bromo-1H-indol-3-yl octanoate is a chromogenic substrate for esterase with C8 activity. 5-Bromo-1H-indol-3-yl octanoate yields a blue precipitate when cleaved.
|
-
- HY-W345102
-
|
Chromogenic Substrates
|
4-Methylumbelliferyl β-cellotrioside, a chromogenic substrate for β-glycosidases, is a cellulose fluorescent derivative .
|
-
- HY-P4202A
-
Suc-AEPF-pNA TFA
|
Chromogenic Substrates
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-W116594
-
|
Chromogenic Substrates
|
X-GalNAc is a chromogenic substrate for for N-acetyl-β-galactosidase, used to determine the presence or absence of a cloned DNA insert in bacteria growing on agar plates .
|
-
- HY-W141825
-
|
Chromogenic Substrates
|
N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .
|
-
- HY-D0908
-
|
Dyes
|
Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins.
|
-
- HY-W337201
-
|
Fluorescent Dyes/Probes
|
5-Bromo-4-chloro-3-indolyl β-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases .
|
-
- HY-15907
-
NSC240867; Benzylamino-NBD
|
Chromogenic Assays
|
BBD (NSC240867) is a biochemical reagent/chromogenic reagent.
|
-
- HY-114958
-
|
Fluorescent Dyes/Probes
|
RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase .
|
-
- HY-15903
-
-
- HY-15905
-
N-Ethyl-N-sulfopropylaniline sodium salt
|
Chromogenic Assays
|
ALPS(N-Ethyl-N-sulfopropylaniline sodium salt) is a bio-chemical reagents/chromogenic reagent.
|
-
- HY-P0021A
-
Spectrozyme PCa; Chromozym Pca diacetate
|
Chromogenic Substrates
|
D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
|
-
- HY-15928
-
Para-nitrophenyl phosphate disodium
|
Chromogenic Substrates
|
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.
|
-
- HY-112276
-
|
Chromogenic Assays
|
Beryllon II is a widely used chromogenic reagent that is used to determine many elements, such as Mo, Mg and Co, and also used for the determination of proteins.
|
-
- HY-15909
-
BCIP p-toluidine salt; X-phosphate p-toluidine salt
|
Chromogenic Substrates
|
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.
|
-
- HY-52112
-
5-bromo-4-chloroindoxyl acetate
|
Chromogenic Substrates
|
BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase .
|
-
- HY-15930C
-
BM blue monosulfate; Sure Blue TMB monosulfate
|
Chromogenic Substrates
|
TMB monosulfate is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualizing reagent used in enzyme-linked immunosorbent assays (ELISA).
|
-
- HY-15930
-
BM blue; Sure Blue TMB
|
Chromogenic Substrates
|
TMB (BM blue) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).
|
-
- HY-15930A
-
BM blue dihydrochloride; Sure Blue TMB dihydrochloride
|
Chromogenic Substrates
|
TMB dihydrochloride (BM blue dihydrochloride) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).
|
-
- HY-D1676
-
|
Fluorescent Dyes/Probes
|
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
|
-
- HY-15914
-
DCHBS
|
Chromogenic Substrates
|
DHBS is Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions.
|
-
- HY-P4039
-
|
Chromogenic Substrates
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
-
- HY-W411361
-
PCNPH
|
Chromogenic Substrates
|
Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone (PCNPH) is a chromogenic substrate to peroxidase enzymes. Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone can form a purple indamine dye with peroxidase enzymes and peroxides .
|
-
- HY-15934
-
X-GAL
1 Publications Verification
BCIG
|
Chromogenic Substrates
|
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
|
-
- HY-D1213
-
Dipotassium nitrocatechol sulfate
|
Dyes
|
4-Nitrocatechol sulfate dipotassium salt (Dipotassium nitrocatechol sulfate) is a chromogenic substrate for sulphatase .
|
-
- HY-W154295
-
|
Fluorescent Dyes/Probes
|
Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity .
|
-
- HY-15923
-
|
Fluorescent Dyes/Probes
|
MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium .
|
-
- HY-118320
-
Mordant orange 1
|
Fluorescent Dyes/Probes
|
Alizarine Yellow R (Mordant orange 1), a salicylic acid derivative, is a azo dye. Alizarine Yellow R is mostly used as a pH indicator, as a biological stain in chemical examinations and also in dyeing industries .
|
-
- HY-W247131
-
|
Fluorescent Dyes/Probes
|
DASPEI is a cationic styrenyl mitochondrial dye with large Stokes shift. DASPEI has excitation and emission wavelength at 550/573 nm, which has good light chromogenic property. DASPEI can stain mitochondria in living cells with good labeling property. And DASPEI can also be used to stain presynaptic nerve endings independently of neuronal activity .
|
-
- HY-D1266
-
NO-red
|
Fluorescent Dyes/Probes
|
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .
|
-
- HY-14536
-
Basic Blue 9; CI-52015; Methylthioninium chloride
|
Chromogenic Assays
|
Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation .
|
-
- HY-15902
-
AzBTS-(NH4)2
|
Chromogenic Substrates
|
ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.
|
-
- HY-15924
-
Thiazolyl Blue
Maximum Cited Publications
99 Publications Verification
MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide
|
Chromogenic Substrates
|
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .
|
-
- HY-15925
-
NBT
|
Chromogenic Substrates
|
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .
|
-
- HY-15931
-
TMBZ-PS
|
Chromogenic Substrates
|
TMB-PS(102062-36-2) is N-(3-sulfopropyl)-3,3',5,5'-tetramenthylbenzidine sodium salt; White - pale yellow crystalline powder, soluble in water, can be used under neutral, acidic and alkaline conditions.
|
-
- HY-15935
-
|
Chromogenic Assays
|
X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) .
|
-
- HY-D0711
-
Foxgreen; IC Green; Cardiogreen
|
Chromogenic Assays
|
Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
|
-
- HY-16710
-
GPN; Glycylproline p-nitroanilide tosylate
|
Chromogenic Substrates
|
GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay.
|
-
- HY-D0717
-
Diaminofluorescein-FM diacetate
|
Chromogenic Assays
|
DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .
|
-
- HY-P0019
-
|
Chromogenic Substrates
|
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
|
-
- HY-P0021
-
Chromozym Pca
|
Chromogenic Substrates
|
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).
|
-
- HY-B1046
-
|
Chromogenic Assays
|
Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC50 = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .
|
-
- HY-P0019A
-
|
Chromogenic Substrates
|
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
|
-
- HY-12591
-
D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium
|
Chromogenic Substrates
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-12591A
-
D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
|
Chromogenic Substrates
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-D0055
-
|
Chromogenic Substrates
|
3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that generates blue fluorescent product upon enzyme cleavage
Target: Cytochrome P450
3-Cyano-7-ethoxycoumarin is a fluorescent probe useful in microsomal dealkylase studies.
|
-
- HY-D0829
-
|
Chromogenic Substrates
|
3,6-Dichlorotrimellitic anhydride is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
|
-
- HY-D0828
-
|
Chromogenic Assays
|
3,6-Dichlorotrimellitic acid is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
|
- HY-N0116
-
Natural Black 1; Haematoxylin
|
Chromogenic Substrates
|
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
|
- HY-D0831
-
|
Chromogenic Substrates
|
WST-8 is a water-soluble tetrazolium dye, WST-8 enhances sensitivity of the WST-8-based assay over the conventional MTS-based assay.
|
- HY-D0516
-
Sudan Blue II; Oil Blue 35
|
Chromogenic Assays
|
Solvent Blue 35 (Sudan Blue II; Oil Blue 35) is a dye used for colouring alcoholic and hydrocarbon based solvents. It is used for staining triglycerides in animal tissues.
|
- HY-D0006
-
|
Chromogenic Assays
|
Bathophenanthroline is an agent used for the measurement of iron concentrations in aqueous , serum and urine samples by colorimetry.
|
- HY-12591B
-
D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium
|
Chromogenic Substrates
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
- HY-P1003
-
|
Chromogenic Substrates
|
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
|
- HY-101895
-
FDG
|
Chromogenic Substrates
|
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm).
|
- HY-D0935A
-
MUG
|
Chromogenic Substrates
|
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
|
- HY-D1026
-
3-Carboxyumbelliferyl-β-D-galactopyranoside
|
Chromogenic Substrates
|
CUG (3-Carboxyumbelliferyl-β-D-galactopyranoside) is a fluorogenic substrate (λex=386, λem=445 nm, ε=32K).
|
- HY-D0994
-
4-MUP; MUP
|
Chromogenic Substrates
|
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .
|
- HY-D0995
-
MESG
|
Chromogenic Substrates
|
7-Methyl-6-thioguanosine (MESG) is a chromophoric substrate which can be used for the quantitation of inorganic phosphate. 7-Methyl-6-thioguanosine is also used to determine the activity of purine nucleoside phosphorylase .
|
- HY-111377
-
|
Chromogenic Assays
|
Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group .
|
- HY-P1448
-
- HY-112641A
-
|
Chromogenic Substrates
|
AkaLumine hydrochloride is a luciferin analogue, with a Km of 2.06 μM for recombinant Fluc protein.
|
- HY-111653
-
CycLuc1
1 Publications Verification
|
Chromogenic Substrates
|
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
|
- HY-D0144
-
Methoxyresorufin
|
Chromogenic Substrates
|
Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .
|
- HY-D0145
-
Resorufin ethyl ether
|
Chromogenic Substrates
|
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase .
|
- HY-19948
-
TRx0237 mesylate; Methylene blue leuco base mesylate
|
Chromogenic Assays
|
Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes .
|
- HY-129096
-
|
Chromogenic Substrates
|
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+) .
|
- HY-P3363
-
|
Chromogenic Substrates
|
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
|
- HY-146248
-
|
Chromogenic Substrates
|
TFMU-ADPr is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr has excellent reactivity, generality, stability, and usability. TFMU-ADPr is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes .
|
- HY-D1505
-
|
Chromogenic Assays
|
4-(N,N-Dimethylamino)azobenzene-4'-isothiocyanate is a chromophoric, hydrophobic reagent for probing membrane-buried segments of intrinsic proteins .
|
- HY-D1582
-
|
Chromogenic Substrates
|
C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .
|
- HY-D1647
-
|
Chromogenic Substrates
|
7-Hydroxycoumarinyl-γ-linolenate is a cytosolic phospholipase A2 (cPLA2) fluorogenic substrate. 7-Hydroxycoumarinyl-γ-linolenate can be used to monitor the enzymatic activity of cPLA2 .
|
- HY-D1634
-
|
Chromogenic Substrates
|
Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM -1s -1. The high concentration of BZ-FVR-AMC inhibits the substrate .
|
- HY-P1093
-
|
Chromogenic Substrates
|
Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase .
|
- HY-P2614
-
- HY-P2685
-
|
Chromogenic Substrates
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase .
|
- HY-P3098
-
|
Chromogenic Substrates
|
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .
|
- HY-P3120
-
|
Chromogenic Substrates
|
Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).
|
- HY-P2616
-
|
Chromogenic Substrates
|
Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2) .
|
- HY-D0994A
-
4-MUP disodium; MUP disodium
|
Chromogenic Substrates
|
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .
|
- HY-148073
-
- HY-D1670
-
- HY-D1208
-
|
Chromogenic Substrates
|
CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .
|
- HY-W354821
-
- HY-W357142
-
- HY-W010991
-
Cat. No. |
Product Name |
Type |
-
- HY-15932
-
TOOS sodium salt
|
Biochemical Assay Reagents
|
TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .
|
-
- HY-15927
-
|
Enzyme Substrates
|
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside can be used to measure of β-glucosidase activity .
|
-
- HY-137779
-
|
Biochemical Assay Reagents
|
5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside, a chromogenic substrate for the detection of β-galactosidase activity. It is commonly used in molecular biology techniques such as gene expression analysis and reporter gene analysis. When β-galactosidase cleaves X-Gluc, a blue precipitate is produced, which can be observed by microscopy or other detection methods. X-Gluc has high sensitivity and specificity for the detection of β-galactosidase activity, making it a widely used tool in molecular biology research.
|
-
- HY-157926
-
|
Chelators
|
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe 2+), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe 2+) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >) .
|
-
- HY-W127380
-
|
Biochemical Assay Reagents
|
Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.
|
-
- HY-D1208
-
|
Chromogenic Substrates
|
CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4202
-
Suc-AEPF-pNA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-P4202A
-
Suc-AEPF-pNA TFA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-P10083
-
-
- HY-P10094
-
|
Fluorescent Dye
|
Others
|
β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
|
-
- HY-P4458
-
|
Ser/Thr Protease
|
Cancer
|
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
|
-
- HY-P3949
-
|
Fluorescent Dye
|
Others
|
Fluorescent Substrate for Glu-Specific Proteases is a V8 protease-Specific chromogenic substrate .
|
-
- HY-P4518
-
|
Ser/Thr Protease
|
Others
|
Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
|
-
- HY-P4484
-
|
Peptides
|
Others
|
Suc-AAPK-pNA is a chromogenic substrate for the determination of serine/threonine kinase activity and enzyme kinetic parameters .
|
-
- HY-P4475
-
-
- HY-P4517
-
|
Peptides
|
Others
|
Z-Tyr-Lys-Arg-pNA is a chromogenic substrate. Z-Tyr-Lys-Arg-pNA can be used to detect the activity of subtilisin-type and yapsin-like proteases .
|
-
- HY-P4460
-
|
Ser/Thr Protease
|
Cancer
|
AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
|
-
- HY-P4482
-
|
Bacterial
|
Infection
|
Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
|
-
- HY-P4464
-
|
Ser/Thr Protease
|
Cancer
|
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
|
-
- HY-P4470
-
|
Ser/Thr Protease
|
Cancer
|
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
|
-
- HY-P3934
-
|
HIV Protease
|
Infection
|
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .
|
-
- HY-P0021A
-
Spectrozyme PCa; Chromozym Pca diacetate
|
Fluorescent Dye
|
Others
|
D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
|
-
- HY-P4039
-
|
HCV Protease
|
Infection
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
-
- HY-P2573
-
Suc-Ala-Ala-Pro-Phe-pNA
|
Peptides
|
Others
|
Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils .
|
-
- HY-123275A
-
S-2238 hydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
|
-
- HY-123275
-
S-2238
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
|
-
- HY-123275C
-
S-2238 dihydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
|
-
- HY-123275B
-
S-2238 acetate
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
|
-
- HY-P0022
-
-
- HY-P0022A
-
-
- HY-126809
-
|
Peptides
|
Others
|
Chromozym PK is a Chromogenic Substrate and can be used in? Factor XII assay .
|
-
- HY-P5278
-
|
Peptides
|
Others
|
Z-Gly-Arg-Thiobenzyl ester is a chromogenic substrate for plasmogen-activated serine proteases .
|
-
- HY-P6027
-
|
Peptides
|
Others
|
H-D-CHA-Ala-Arg-pNA is a chromogenic substrate for the amidolytic assay .
|
-
- HY-P3936
-
|
Fluorescent Dye
|
Others
|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
|
-
- HY-P3126
-
|
Factor Xa
|
Others
|
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
|
-
- HY-P10059
-
|
Peptides
|
Others
|
Boc-Val-Gly-Arg-βNA is a colorimetric substrate for plasminogen activator .
|
-
- HY-P10145
-
|
Peptides
|
Others
|
Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .
|
-
- HY-P4491
-
|
Peptides
|
Others
|
Suc-Leu-Leu-Val-Tyr-pNA is a chymotrypsin-like chromogenic substrate that can be used to detect chymotrypsin enzymatic activity .
|
-
- HY-P0020
-
tos-GPR-ANBA-IPA
|
Biochemical Assay Reagents
|
Others
|
Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA can be used for luminescence measurement .
|
-
- HY-P4453
-
|
Caspase
|
Cancer
|
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
|
-
- HY-P10005
-
|
Peptides
|
Cardiovascular Disease
|
D-Val-Gly-Arg-pNA is a chromogenic substrate of TPA (tissue plasminogen activator). D-Val-Gly-Arg-pNA can be used to detect the amidolytic activity of TPA I and TPA II .
|
-
- HY-P6027A
-
|
Fluorescent Dye
|
Others
|
H-D-CHA-Ala-Arg-pNA (diacetate) is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-150523). H-D-CHA-Ala-Arg-pNA (diacetate) is a chromogenic substrate for the amidolytic assay .
|
-
- HY-P3480
-
|
Fluorescent Dye
|
Others
|
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
|
-
- HY-P4516
-
|
Peptides
|
Cancer
|
Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer .
|
-
- HY-P4404
-
|
Peptides
|
Others
|
Abz-GIVRAK(Dnp) is the most efficient substrate for cathepsin B and is highly selective for this enzyme among lysosomal cysteine proteases. After Abz-GIVRAK(Dnp) is hydrolyzed, aminoacylbenziminosulfosuccinic acid (Abz-SAS) is released, and dinitrobenzoyl (Dnp) is also released. The product of this hydrolysis reaction, Abz-SAS, is fluorescent under ultraviolet light and can emit a fluorescent signal .
|
-
- HY-P0019
-
-
- HY-P0021
-
Chromozym Pca
|
Fluorescent Dye
|
Others
|
D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).
|
-
- HY-P0019A
-
|
Fluorescent Dye
|
Others
|
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
|
-
- HY-P1003
-
|
Fluorescent Dye
|
Others
|
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
|
-
- HY-P1448
-
-
- HY-P3363
-
|
Caspase
|
Cancer
|
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
|
-
- HY-P2614
-
|
Caspase
|
Others
|
Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3 .
|
-
- HY-P2685
-
|
Fluorescent Dye
|
Others
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase .
|
-
- HY-P3098
-
|
MMP
|
Others
|
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .
|
-
- HY-P3120
-
|
MMP
|
Others
|
Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).
|
-
- HY-P2616
-
- HY-W010991
-
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-12591A
-
D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
|
Natural Products
Animals
Source classification
Other Diseases
Disease Research Fields
|
Fluorescent Dye
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
-
- HY-N0116
-
-
-
- HY-113245
-
-
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: