Z-Gly-Arg-Thiobenzyl ester
Based on 1 Customer Validation
Z-Gly-Arg-Thiobenzyl ester is a synthetic peptide substrate used to detect the cleavage activity of C1r. Z-Gly-Arg-Thiobenzyl ester can be cleaved by proteases such as C1r, and when used in combination with DTNB (HY-15915) , it enables colorimetric determination of protease activity, which can be applied to enzymological studies related to the complement system.
For research use only. We do not sell to patients.
- Purity: 98.93%
- CAS No.: 130698-88-3
- Formula: C23H29N5O4S
- Molecular Weight:471.57
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Z-Gly-Arg-Thiobenzyl ester (300 µM; 1 h), as a substrate of C1r, can be used in combination with DTNB to determine the protease activity of C1r via a colorimetric assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 130698-88-3
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Appearance Solid
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Molecular Weight 471.57
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Formula C23H29N5O4S
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Color White to off-white
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Sequence
{Z}-Gly-Arg-{Thiobenzyl ester}
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Sequence Shortening
{Z}-GR-{Thiobenzyl ester}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (212.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1206 mL | 10.6029 mL | 21.2058 mL | 53.0144 mL |
| 5 mM | 0.4241 mL | 2.1206 mL | 4.2412 mL | 10.6029 mL | |
| 10 mM | 0.2121 mL | 1.0603 mL | 2.1206 mL | 5.3014 mL | |
| 15 mM | 0.1414 mL | 0.7069 mL | 1.4137 mL | 3.5343 mL | |
| 20 mM | 0.1060 mL | 0.5301 mL | 1.0603 mL | 2.6507 mL | |
| 25 mM | 0.0848 mL | 0.4241 mL | 0.8482 mL | 2.1206 mL | |
| 30 mM | 0.0707 mL | 0.3534 mL | 0.7069 mL | 1.7671 mL | |
| 40 mM | 0.0530 mL | 0.2651 mL | 0.5301 mL | 1.3254 mL | |
| 50 mM | 0.0424 mL | 0.2121 mL | 0.4241 mL | 1.0603 mL | |
| 60 mM | 0.0353 mL | 0.1767 mL | 0.3534 mL | 0.8836 mL | |
| 80 mM | 0.0265 mL | 0.1325 mL | 0.2651 mL | 0.6627 mL | |
| 100 mM | 0.0212 mL | 0.1060 mL | 0.2121 mL | 0.5301 mL |