1. pGlu-Pro-Arg-MNA monoacetate

pGlu-Pro-Arg-MNA monoacetate 

Cat. No.: HY-P0022A Purity: ≥99.0%
COA Handling Instructions

pGlu-Pro-Arg-MNA monoacetate is a chromogenic substrate.

For research use only. We do not sell to patients.

pGlu-Pro-Arg-MNA monoacetate Chemical Structure

pGlu-Pro-Arg-MNA monoacetate Chemical Structure

CAS No. : 2070009-26-4

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1 mg USD 140 In-stock
5 mg USD 350 In-stock
10 mg USD 550 In-stock
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Other Forms of pGlu-Pro-Arg-MNA monoacetate:

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Description

pGlu-Pro-Arg-MNA monoacetate is a chromogenic substrate.

In Vitro

Protein C activity is measured using the reagents, both with a partial thromboplastin time (aPTT) system as well as with a chromogenic substrate (pGlu-Pro-Arg-mNA) in a photometric method[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

592.60

Formula

C25H36N8O9

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CC(O)=O.O=C1CC[C@@H](C(N2[C@H](C(N[C@@H](CCCNC(N)=N)C(NC3=CC=C([N+]([O-])=O)C=C3OC)=O)=O)CCC2)=O)N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 25 mg/mL (42.19 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6875 mL 8.4374 mL 16.8748 mL
5 mM 0.3375 mL 1.6875 mL 3.3750 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6875 mL 8.4374 mL 16.8748 mL 42.1870 mL
5 mM 0.3375 mL 1.6875 mL 3.3750 mL 8.4374 mL
10 mM 0.1687 mL 0.8437 mL 1.6875 mL 4.2187 mL
15 mM 0.1125 mL 0.5625 mL 1.1250 mL 2.8125 mL
20 mM 0.0844 mL 0.4219 mL 0.8437 mL 2.1093 mL
25 mM 0.0675 mL 0.3375 mL 0.6750 mL 1.6875 mL
30 mM 0.0562 mL 0.2812 mL 0.5625 mL 1.4062 mL
40 mM 0.0422 mL 0.2109 mL 0.4219 mL 1.0547 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
pGlu-Pro-Arg-MNA monoacetate
Cat. No.:
HY-P0022A
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