MeOSuc-Ala-Ala-Pro-Val-pNA

Name: MeOSuc-Ala-Ala-Pro-Val-pNA
Brand: MedChemExpress
SKU: HY-P2685
Rating: 4.5 (1 reviews)

Cat. No.: HY-P2685 Purity: 98.27%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

MeOSuc-Ala-Ala-Pro-Val-pNA Chemical Structure

CAS No. : 70967-90-7

Size	Price	Stock	Quantity
5 mg	USD 45	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase^[1].

In Vitro

MeOSuc-Ala-Ala-Pro-Val-pNA exhibits k_c/K_m values of 185,000, 15,000, 58,000 and 330,000 M^-1s^-1 at 0.10 M phosphate, 0.20 M Mes, 0.10 M phosphate and 0.04 M phosphate, respectively, for reactions of human leukocyte elastase^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

590.63

Formula

C₂₇H₃₈N₆O₉

CAS No.

70967-90-7

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (169.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6931 mL	8.4655 mL	16.9311 mL
5 mM	0.3386 mL	1.6931 mL	3.3862 mL
10 mM	0.1693 mL	0.8466 mL	1.6931 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.27%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (248 KB) RP-HPLC (109 KB) MS (216 KB)

Handling Instructions (2659 KB)

References

[1]. Castillo MJ, et al. Sensitive substrates for human leukocyte and porcine pancreatic elastase: a study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases. Anal Biochem. 1979 Oct 15;99(1):53-64. [Content Brief]

[2]. Ross L. Stein, et al. Catalysis by human leukocyte elastase. Rate-limiting deacylation for specific p-nitroanilides and amides. J. Am. Chem. Soc. 1984, 106, 3, 796-798.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6931 mL	8.4655 mL	16.9311 mL	42.3277 mL
	5 mM	0.3386 mL	1.6931 mL	3.3862 mL	8.4655 mL
	10 mM	0.1693 mL	0.8466 mL	1.6931 mL	4.2328 mL
	15 mM	0.1129 mL	0.5644 mL	1.1287 mL	2.8218 mL
	20 mM	0.0847 mL	0.4233 mL	0.8466 mL	2.1164 mL
	25 mM	0.0677 mL	0.3386 mL	0.6772 mL	1.6931 mL
	30 mM	0.0564 mL	0.2822 mL	0.5644 mL	1.4109 mL
	40 mM	0.0423 mL	0.2116 mL	0.4233 mL	1.0582 mL
	50 mM	0.0339 mL	0.1693 mL	0.3386 mL	0.8466 mL
	60 mM	0.0282 mL	0.1411 mL	0.2822 mL	0.7055 mL
	80 mM	0.0212 mL	0.1058 mL	0.2116 mL	0.5291 mL
	100 mM	0.0169 mL	0.0847 mL	0.1693 mL	0.4233 mL