N-(p-Tosyl)-GPR-pNA acetate (Synonyms: Chromozym-TH)

Cat. No.: HY-138143 Pureza: 99.68%: Ficha de datos
COA

SDS
Instrucciones de manejo
FAQs
Technical Support

N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V).

Para uso exclusivo en investigación. No vendemos a pacientes.

N-(p-Tosyl)-GPR-pNA acetate Estructura química

No. CAS : 86890-95-1

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

or Consulta para venta a granel

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Recomendaciones destacadas

•Related Small Molecules:

•Related Proteins:

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

IC₅₀ & Target

Hirunorm IV, Hirunorm V^[1]

Peso molecular

662.71

Fòrmula

C₂₈H₃₈N₈O₉S

No. CAS

86890-95-1

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C([C@H](CCC1)N1C(CN[S](=O)(C(C=C2)=CC=C2C)=O)=O)N[C@@H](CCCNC(N)=N)C(NC(C=C3)=CC=C3[N](=O)=O)=O.CC(O)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

DMSO : 100 mg/mL (150.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5090 mL	7.5448 mL	15.0896 mL
5 mM	0.3018 mL	1.5090 mL	3.0179 mL
10 mM	0.1509 mL	0.7545 mL	1.5090 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.9%

Select Batch:

Ficha de datos (274 KB) SDS (252 KB)

COA (253 KB) Elemental Analysis Report (113 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Cappiello M, et al. Kinetics of human thrombin inhibition by two novel peptide inhibitors (Hirunorm IV and Hirunorm V). Biochem Pharmacol. 1996 Oct 25;52(8):1141-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5090 mL	7.5448 mL	15.0896 mL	37.7239 mL
	5 mM	0.3018 mL	1.5090 mL	3.0179 mL	7.5448 mL
	10 mM	0.1509 mL	0.7545 mL	1.5090 mL	3.7724 mL
	15 mM	0.1006 mL	0.5030 mL	1.0060 mL	2.5149 mL
	20 mM	0.0754 mL	0.3772 mL	0.7545 mL	1.8862 mL
	25 mM	0.0604 mL	0.3018 mL	0.6036 mL	1.5090 mL
	30 mM	0.0503 mL	0.2515 mL	0.5030 mL	1.2575 mL
	40 mM	0.0377 mL	0.1886 mL	0.3772 mL	0.9431 mL
	50 mM	0.0302 mL	0.1509 mL	0.3018 mL	0.7545 mL
	60 mM	0.0251 mL	0.1257 mL	0.2515 mL	0.6287 mL
	80 mM	0.0189 mL	0.0943 mL	0.1886 mL	0.4715 mL
	100 mM	0.0151 mL	0.0754 mL	0.1509 mL	0.3772 mL

N-(p-Tosyl)-GPR-pNA acetate Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-(p-Tosyl)-GPR-pNA86890-95-1Chromozym-THFluorescent DyeInhibitorinhibitorinhibit

Productos vistos recientemente:

Nombre del producto

Requested Quantity *

Nombre del solicitante *

Saludo

Direcciòn del E-mail *

Número de teléfono *

Department

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

Observaciones

Nombre del producto

Lot #

Nombre del solicitante *

Direcciòn del E-mail *

Número de teléfono

Department *

Nombre de la Organizaciòn *

Country or Region *

Observaciones

Name
E-mail *

	Sorry, but the email address you supplied was invalid.

N-(p-Tosyl)-GPR-pNA acetate (Synonyms: Chromozym-TH)

N-(p-Tosyl)-GPR-pNA acetate Related Antibodies

Recomendaciones destacadas

•Related Small Molecules:

•Related Proteins:

Actividad biológica

Pureza y Documentación

Referencias

Revisión del cliente

Calculadora de molaridad

Calculadora de dilución