N-(p-Tosyl)-GPR-pNA acetate
Based on 1 Customer Validation
N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V).
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 86890-95-1
- Formula: C28H38N8O9S
- Molecular Weight:662.71
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Hirunorm IV, Hirunorm V[1]
Chemical Information
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CAS No. 86890-95-1
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Appearance Solid
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Molecular Weight 662.71
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Formula C28H38N8O9S
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Color Off-white to light yellow
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SMILES
O=C([C@H](CCC1)N1C(CN[S](=O)(C(C=C2)=CC=C2C)=O)=O)N[C@@H](CCCNC(N)=N)C(NC(C=C3)=CC=C3[N](=O)=O)=O.CC(O)=O
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Synonyms
Chromozym-TH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (150.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5090 mL | 7.5448 mL | 15.0896 mL | 37.7239 mL |
| 5 mM | 0.3018 mL | 1.5090 mL | 3.0179 mL | 7.5448 mL | |
| 10 mM | 0.1509 mL | 0.7545 mL | 1.5090 mL | 3.7724 mL | |
| 15 mM | 0.1006 mL | 0.5030 mL | 1.0060 mL | 2.5149 mL | |
| 20 mM | 0.0754 mL | 0.3772 mL | 0.7545 mL | 1.8862 mL | |
| 25 mM | 0.0604 mL | 0.3018 mL | 0.6036 mL | 1.5090 mL | |
| 30 mM | 0.0503 mL | 0.2515 mL | 0.5030 mL | 1.2575 mL | |
| 40 mM | 0.0377 mL | 0.1886 mL | 0.3772 mL | 0.9431 mL | |
| 50 mM | 0.0302 mL | 0.1509 mL | 0.3018 mL | 0.7545 mL | |
| 60 mM | 0.0251 mL | 0.1257 mL | 0.2515 mL | 0.6287 mL | |
| 80 mM | 0.0189 mL | 0.0943 mL | 0.1886 mL | 0.4715 mL | |
| 100 mM | 0.0151 mL | 0.0754 mL | 0.1509 mL | 0.3772 mL |
N-(p-Tosyl)-GPR-pNA acetate Related Classifications
HY-138143 Related Classifications
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