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  2. L-Leucine-7-amido-4-methylcoumarin hydrochloride

L-Leucine-7-amido-4-methylcoumarin hydrochloride (Synonyms: Leu-AMC hydrochloride)

Cat. No.: HY-137844
Handling Instructions

L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro.

For research use only. We do not sell to patients.

L-Leucine-7-amido-4-methylcoumarin hydrochloride Chemical Structure

L-Leucine-7-amido-4-methylcoumarin hydrochloride Chemical Structure

CAS No. : 62480-44-8

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Description

L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro[1].

In Vitro

In leucine aminopeptidases inhibition assays in KB 3.1 cells. Compounds 3 and 5 are observed to weakly inhibit the biofilm formation by S. aureus and constrain inhibitory activity of ʟ-Leu-AMC hydrolysis in KB 3.1 cells[1].
The amount of hydrolyzed 7-amino-4-methylcoumarin (AMC) is determined in a fluorescence spectrophotometer (excitation/emission: 365/440 nm)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

324.80

Formula

C₁₆H₂₁ClN₂O₃

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
L-Leucine-7-amido-4-methylcoumarin hydrochloride
Cat. No.:
HY-137844
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