4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside
Based on 1 publication(s) in Google Scholar
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase.
For research use only. We do not sell to patients.
- Purity : 99.95%
- CAS No.: 37067-30-4
- Formula: C18H21NO8
- Molecular Weight:379.36
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications Citing Use of MedChemExpress (MCE) 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside
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Biological Activity
Description
In Vitro
The enzyme functionality is assessed by its ability remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 37067-30-4
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Appearance Solid
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Molecular Weight 379.36
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Formula C18H21NO8
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Color White to off-white
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SMILES
CC(N[C@H]([C@H]([C@@H]1O)O)[C@@H](O[C@@H]1CO)OC2=CC=C(C(C)=C3)C(OC3=O)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Proteome Res
Proteome and Glycoproteome Analyses Reveal Regulation of Protein Glycosylation Site-Specific Occupancy and Lysosomal Hydrolase Maturation by N-Glycan-Dependent ER-Quality Control. [Abstract]2024 Oct 4;23(10):4409-4421. PMID: 39235835
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (131.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6360 mL | 13.1801 mL | 26.3602 mL | 65.9005 mL |
| 5 mM | 0.5272 mL | 2.6360 mL | 5.2720 mL | 13.1801 mL | |
| 10 mM | 0.2636 mL | 1.3180 mL | 2.6360 mL | 6.5900 mL | |
| 15 mM | 0.1757 mL | 0.8787 mL | 1.7573 mL | 4.3934 mL | |
| 20 mM | 0.1318 mL | 0.6590 mL | 1.3180 mL | 3.2950 mL | |
| 25 mM | 0.1054 mL | 0.5272 mL | 1.0544 mL | 2.6360 mL | |
| 30 mM | 0.0879 mL | 0.4393 mL | 0.8787 mL | 2.1967 mL | |
| 40 mM | 0.0659 mL | 0.3295 mL | 0.6590 mL | 1.6475 mL | |
| 50 mM | 0.0527 mL | 0.2636 mL | 0.5272 mL | 1.3180 mL | |
| 60 mM | 0.0439 mL | 0.2197 mL | 0.4393 mL | 1.0983 mL | |
| 80 mM | 0.0330 mL | 0.1648 mL | 0.3295 mL | 0.8238 mL | |
| 100 mM | 0.0264 mL | 0.1318 mL | 0.2636 mL | 0.6590 mL |