4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside

Name: 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside
Brand: MedChemExpress
SKU: HY-137853
Rating: 4.5 (1 reviews)

Cat. No.: HY-137853 Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
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Technical Support

4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside 화학구조

CAS No. : 37067-30-4

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	견적 받기
1 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside

•J Proteome Res. 2024 Oct 4;23(10):4409-4421. [Abstract]

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase^[1].

In Vitro

The enzyme functionality is assessed by its ability remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

379.36

화학식

C₁₈H₂₁NO₈

CAS No.

37067-30-4

Appearance

Solid

Color

White to off-white

SMILES

CC(N[C@H]([C@H]([C@@H]1O)O)[C@@H](O[C@@H]1CO)OC2=CC=C(C(C)=C3)C(OC3=O)=C2)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도

In Vitro:

DMSO : 50 mg/mL (131.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6360 mL	13.1801 mL	26.3602 mL
5 mM	0.5272 mL	2.6360 mL	5.2720 mL
10 mM	0.2636 mL	1.3180 mL	2.6360 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.95%

Select Batch:

Data Sheet (274 KB) SDS (393 KB)

COA (251 KB) HNMR (267 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Li J, et, al. Identification of a specific inhibitor of nOGA - a caspase-3 cleaved O-GlcNAcase variant during apoptosis. Biochemistry (Mosc). 2012 Feb;77(2):194-200. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6360 mL	13.1801 mL	26.3602 mL	65.9005 mL
	5 mM	0.5272 mL	2.6360 mL	5.2720 mL	13.1801 mL
	10 mM	0.2636 mL	1.3180 mL	2.6360 mL	6.5900 mL
	15 mM	0.1757 mL	0.8787 mL	1.7573 mL	4.3934 mL
	20 mM	0.1318 mL	0.6590 mL	1.3180 mL	3.2950 mL
	25 mM	0.1054 mL	0.5272 mL	1.0544 mL	2.6360 mL
	30 mM	0.0879 mL	0.4393 mL	0.8787 mL	2.1967 mL
	40 mM	0.0659 mL	0.3295 mL	0.6590 mL	1.6475 mL
	50 mM	0.0527 mL	0.2636 mL	0.5272 mL	1.3180 mL
	60 mM	0.0439 mL	0.2197 mL	0.4393 mL	1.0983 mL
	80 mM	0.0330 mL	0.1648 mL	0.3295 mL	0.8238 mL
	100 mM	0.0264 mL	0.1318 mL	0.2636 mL	0.6590 mL