1. Anti-infection
  2. Antibiotic
  3. Nitrocefin

Nitrocefin 

Cat. No.: HY-108913 Purity: 90.89%
COA Handling Instructions

Nitrocefin is a chromogenic β-lactamase substrate that undergoes distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics.

For research use only. We do not sell to patients.

Nitrocefin Chemical Structure

Nitrocefin Chemical Structure

CAS No. : 41906-86-9

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 187 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 187 In-stock
Solid
5 mg USD 170 In-stock
10 mg USD 290 In-stock
25 mg USD 550 In-stock
50 mg USD 880 In-stock
100 mg USD 1400 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

Nitrocefin is a chromogenic β-lactamase substrate that undergoes distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics[1].

IC50 & Target

β-lactam

 

Molecular Weight

516.50

Appearance

Solid

Formula

C21H16N4O8S2

CAS No.
SMILES

O=C(C(N12)=C(/C=C/C3=CC=C([N+]([O-])=O)C=C3[N+]([O-])=O)CS[[email protected]]2([H])[[email protected]](NC(CC4=CC=CS4)=O)C1=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (193.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9361 mL 9.6805 mL 19.3611 mL
5 mM 0.3872 mL 1.9361 mL 3.8722 mL
10 mM 0.1936 mL 0.9681 mL 1.9361 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Nitrocefin
Cat. No.:
HY-108913
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