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  3. Hexapeptide-9

Hexapeptide-9 is a signaling peptide. Hexapeptide-9 can promote collagen production. Hexapeptide-9 has anti-aging activity, and can be used in cosmetic research.

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Hexapeptide-9

Hexapeptide-9 構造式

CAS 番号 : 885024-94-2

容量 価格(税別) 在庫状況 数量
5 mg $50 在庫あり
10 mg $80 在庫あり
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100 mg   お問い合わせ  

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製品説明

Hexapeptide-9 is a signaling peptide. Hexapeptide-9 can promote collagen production. Hexapeptide-9 has anti-aging activity, and can be used in cosmetic research[1][2][3].

体外実験

Hexapeptide-9 (1-5%; 48 h) can promote the expression of collagen in ex vivo skin tissues[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Hexapeptide-9 (administered transdermally; 8 weeks) exhibits anti-aging activity in a photoaging mouse model. It can reduce ultraviolet-induced oxidative stress, inflammatory response, as well as skin thickening and roughness. It significantly alleviates the increase in MDA caused by ultraviolet exposure, prevents the decline in SOD activity and hydroxyproline levels. The effect is more remarkable when used in combination with GALA (composed of γ-aminobutyric acid and lactic acid). The mechanism involves the activation of the PPAR signaling pathway[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

582.61

分子式

C24H38N8O9

CAS 番号
Appearance

Solid

Color

White to off-white

Sequence Shortening

GPQGPQ

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

polypeptide, sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (polypeptide, sealed storage, away from moisture and light, under nitrogen)

溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (171.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 100 mg/mL (171.64 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7164 mL 8.5821 mL 17.1641 mL
5 mM 0.3433 mL 1.7164 mL 3.4328 mL
10 mM 0.1716 mL 0.8582 mL 1.7164 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

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体積 (開始)

V1

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 1.7164 mL 8.5821 mL 17.1641 mL 42.9104 mL
5 mM 0.3433 mL 1.7164 mL 3.4328 mL 8.5821 mL
10 mM 0.1716 mL 0.8582 mL 1.7164 mL 4.2910 mL
15 mM 0.1144 mL 0.5721 mL 1.1443 mL 2.8607 mL
20 mM 0.0858 mL 0.4291 mL 0.8582 mL 2.1455 mL
25 mM 0.0687 mL 0.3433 mL 0.6866 mL 1.7164 mL
30 mM 0.0572 mL 0.2861 mL 0.5721 mL 1.4303 mL
40 mM 0.0429 mL 0.2146 mL 0.4291 mL 1.0728 mL
50 mM 0.0343 mL 0.1716 mL 0.3433 mL 0.8582 mL
60 mM 0.0286 mL 0.1430 mL 0.2861 mL 0.7152 mL
80 mM 0.0215 mL 0.1073 mL 0.2146 mL 0.5364 mL
100 mM 0.0172 mL 0.0858 mL 0.1716 mL 0.4291 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
Hexapeptide-9
製品番号:
HY-P3163
数量:
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