IL-17 modulator 1 disodium

Cat. No.: HY-141535A Purity: 98.38%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

IL-17 modulator 1 (disodium) is an orally active, highly efficacious IL-17 modulator extracted from patent WO 2020127685. IL-17 modulator 1 (disodium) can be used for the research of diseases including psoriasis, ankylosing spondylitis and psoriatic arthritis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

IL-17 modulator 1 disodium 화학구조

CAS No. : 2446803-91-2

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
1 mg	해외재고보유	Estimated Time of Arrival: December 31
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of IL-17 modulator 1 disodium:

IL-17 modulator 4 In-stock
IL-17 modulator 1 견적 받기

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•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Interleukin Related Isoform Specific Products:

View All Isoforms

IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target^[1]

IL-17

분자량

628.57

화학식

C₂₈H₃₅N₆Na₂O₆P

CAS No.

2446803-91-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=NN1C(C)C)N[C@H](C(NC2=CC=C(C3=C(N(N=C3C)COP(O[Na])(O[Na])=O)C)C=C2)=O)C(C4CC4)C5CC5

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 20 mg/mL (31.82 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5909 mL	7.9546 mL	15.9091 mL
5 mM	0.3182 mL	1.5909 mL	3.1818 mL
10 mM	0.1591 mL	0.7955 mL	1.5909 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.38%

Select Batch:

Data Sheet (269 KB) SDS (252 KB)

COA (251 KB) HNMR (191 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. WO 2020127685

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5909 mL	7.9546 mL	15.9091 mL	39.7728 mL
	5 mM	0.3182 mL	1.5909 mL	3.1818 mL	7.9546 mL
	10 mM	0.1591 mL	0.7955 mL	1.5909 mL	3.9773 mL
	15 mM	0.1061 mL	0.5303 mL	1.0606 mL	2.6515 mL
	20 mM	0.0795 mL	0.3977 mL	0.7955 mL	1.9886 mL
	25 mM	0.0636 mL	0.3182 mL	0.6364 mL	1.5909 mL
	30 mM	0.0530 mL	0.2652 mL	0.5303 mL	1.3258 mL