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  5. Lacto-N-fucopentaose II

Lacto-N-fucopentaose II  (Synonyms: LNFP II)

Cat. No.: HY-N7575 Pureza: 98.0%
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Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy.

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Lacto-N-fucopentaose II

Lacto-N-fucopentaose II Estructura química

No. CAS : 21973-23-9

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100 mg   Obtener un presupuesto  

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Lacto-N-fucopentaose II Related Antibodies

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Descripciòn

Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy[1].

IC50 & Target

Human Endogenous Metabolite

 

Peso molecular

853.77

Fòrmula

C32H55NO25
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]([C@@H]([C@@H]([C@@H](O1)C)O)O)[C@@H]1O[C@H]([C@H](O[C@H]([C@@H]2NC(C)=O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@@H]3O)CO)O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O)CO)[C@@H]2O[C@@H]4O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O)CO
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad
In Vitro: 

H2O : 250 mg/mL (292.82 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1713 mL 5.8564 mL 11.7128 mL
5 mM 0.2343 mL 1.1713 mL 2.3426 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.1713 mL 5.8564 mL 11.7128 mL 29.2819 mL
5 mM 0.2343 mL 1.1713 mL 2.3426 mL 5.8564 mL
10 mM 0.1171 mL 0.5856 mL 1.1713 mL 2.9282 mL
15 mM 0.0781 mL 0.3904 mL 0.7809 mL 1.9521 mL
20 mM 0.0586 mL 0.2928 mL 0.5856 mL 1.4641 mL
25 mM 0.0469 mL 0.2343 mL 0.4685 mL 1.1713 mL
30 mM 0.0390 mL 0.1952 mL 0.3904 mL 0.9761 mL
40 mM 0.0293 mL 0.1464 mL 0.2928 mL 0.7320 mL
50 mM 0.0234 mL 0.1171 mL 0.2343 mL 0.5856 mL
60 mM 0.0195 mL 0.0976 mL 0.1952 mL 0.4880 mL
80 mM 0.0146 mL 0.0732 mL 0.1464 mL 0.3660 mL
100 mM 0.0117 mL 0.0586 mL 0.1171 mL 0.2928 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Lacto-N-fucopentaose II Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lacto-N-fucopentaose II21973-23-9LNFP IIEndogenous Metabolitebiliopancreatic malignancymonosialo-ganglioside/glycolipid and sialyl derivativesialyl-LewisInhibitorinhibitorinhibit

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