2. Others Metabolic Enzyme/Protease
  3. Biochemical Assay Reagents Endogenous Metabolite
  4. Lactyl-CoA

Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers.

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Lactyl-CoA

Lactyl-CoA 構造式

CAS 番号 : 1926-57-4

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 3039 在庫あり
Solution
10 mM * 1 mL in DMSO USD 3039 在庫あり
Solid
1 mg $732 在庫あり
5 mg $1645 在庫あり
10 mg $2460 在庫あり
25 mg $4435 在庫あり
50 mg $6210 在庫あり
100 mg   お問い合わせ  
200 mg   お問い合わせ  

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Based on 4 publication(s) in Google Scholar

Other Forms of Lactyl-CoA:

Lactyl-CoA 関連抗体

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製品説明

Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers[1][2].

体外実験

GTPSCS can be used as Lactyl-CoA synthetase, which can convert lactic acid into Lactyl-CoA and provide substrate for histone lactation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lactyl-CoA 関連抗体
分子量

839.60

分子式

C24H40N7O18P3S
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

CC(O)C(SCCNC(CCNC([C@H](O)C(C)(C)COP(OP(O)(OC[C@H]1O[C@@H](N(C=N2)C3=C2C(N)=NC=N3)[C@H](O)[C@@H]1OP(O)(O)=O)=O)(O)=O)=O)=O)=O
輸送条件

Shipping with dry ice.
保管条件

-80°C, protect from light, stored under nitrogen
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (119.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (59.55 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1910 mL 5.9552 mL 11.9104 mL
5 mM 0.2382 mL 1.1910 mL 2.3821 mL
10 mM 0.1191 mL 0.5955 mL 1.1910 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (2.98 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (2.98 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 98.01%

COA (245 KB) HNMR (236 KB) RP-HPLC (301 KB) MS (71 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.1910 mL 5.9552 mL 11.9104 mL 29.7761 mL
5 mM 0.2382 mL 1.1910 mL 2.3821 mL 5.9552 mL
10 mM 0.1191 mL 0.5955 mL 1.1910 mL 2.9776 mL
15 mM 0.0794 mL 0.3970 mL 0.7940 mL 1.9851 mL
20 mM 0.0596 mL 0.2978 mL 0.5955 mL 1.4888 mL
25 mM 0.0476 mL 0.2382 mL 0.4764 mL 1.1910 mL
30 mM 0.0397 mL 0.1985 mL 0.3970 mL 0.9925 mL
40 mM 0.0298 mL 0.1489 mL 0.2978 mL 0.7444 mL
50 mM 0.0238 mL 0.1191 mL 0.2382 mL 0.5955 mL
DMSO 60 mM 0.0199 mL 0.0993 mL 0.1985 mL 0.4963 mL
80 mM 0.0149 mL 0.0744 mL 0.1489 mL 0.3722 mL
100 mM 0.0119 mL 0.0596 mL 0.1191 mL 0.2978 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Lactyl-CoA Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lactyl-CoA1926-57-4Biochemical Assay ReagentsEndogenous Metaboliteacyl-CoAlactic acidInhibitorinhibitorinhibit

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製品名:
Lactyl-CoA
製品番号:
HY-141540
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