2. Protein Tyrosine Kinase/RTK
  3. c-Met/HGFR
  4. Mefatinib free base

Mefatinib free base  (Synonyms: Mifanertinib)

Cat. No.: HY-152852 Purity: 99.40%
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Mefatinib free base is a potent tyrosine kinase inhibitor with antineoplastic activity.

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Mefatinib free base

Mefatinib free base 화학구조

CAS No. : 1639014-72-4

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Mefatinib free base:

Mefatinib free base Related Antibodies

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  • Biological Activity

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제품 설명

Mefatinib free base is a potent tyrosine kinase inhibitor with antineoplastic activity[1].

분자량

465.86

화학식

C21H19ClF3N5O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1OC(F)F)/C=C/CN(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : ≥ 50 mg/mL (107.33 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1466 mL 10.7328 mL 21.4657 mL
5 mM 0.4293 mL 2.1466 mL 4.2931 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1466 mL 10.7328 mL 21.4657 mL 53.6642 mL
5 mM 0.4293 mL 2.1466 mL 4.2931 mL 10.7328 mL
10 mM 0.2147 mL 1.0733 mL 2.1466 mL 5.3664 mL
15 mM 0.1431 mL 0.7155 mL 1.4310 mL 3.5776 mL
20 mM 0.1073 mL 0.5366 mL 1.0733 mL 2.6832 mL
25 mM 0.0859 mL 0.4293 mL 0.8586 mL 2.1466 mL
30 mM 0.0716 mL 0.3578 mL 0.7155 mL 1.7888 mL
40 mM 0.0537 mL 0.2683 mL 0.5366 mL 1.3416 mL
50 mM 0.0429 mL 0.2147 mL 0.4293 mL 1.0733 mL
60 mM 0.0358 mL 0.1789 mL 0.3578 mL 0.8944 mL
80 mM 0.0268 mL 0.1342 mL 0.2683 mL 0.6708 mL
100 mM 0.0215 mL 0.1073 mL 0.2147 mL 0.5366 mL
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Mefatinib free base Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mefatinib1639014-72-4Mifanertinibc-Met/HGFRInhibitorinhibitorinhibit

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상품명:
Mefatinib free base
Cat. No.:
HY-152852
수량:
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