Search Result
Results for "
myosin-h-chain-fragment-mouse-acetate-salt
" in MedChemExpress (MCE) Product Catalog:
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- HY-P3479
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Insulin Receptor
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Metabolic Disease
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Insulin (swine) is an orally active insulin derived from pigs. Insulin (swine) when administered orally acts as an antigen to reduce the severity of pancreatic lymphocyte infiltration, but has no metabolic effect on blood glucose levels. Insulin (swine) increases glucose oxidation, stimulates lipogenesis, and lowers blood glucose levels. Insulin (swine) can be used in diabetes research .
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- HY-P1925A
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PI3K
Reactive Oxygen Species (ROS)
Apoptosis
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Cancer
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GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
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- HY-P3469A
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GCGR
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Metabolic Disease
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Dasiglucagon acetate is a human glucagon analog, and can increase plasma glucose. Dasiglucagon can be used in hypoglycemia research .
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- HY-P3432
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Biochemical Assay Reagents
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Others
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DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
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- HY-145632A
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ALT-801 TFA
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GLP Receptor
GCGR
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Metabolic Disease
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Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .
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- HY-P10204
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Wnt
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Cancer
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FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC50 value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .
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- HY-P4890
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- HY-P10693
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- HY-P11246
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RXFP Receptor
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Metabolic Disease
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A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a Ki value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (Ki = 602.56 nM) and an inhibitory effect on cAMP (EC50) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC50 of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .
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- HY-P6013A
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Calcium Channel
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Others
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wt hMLN (TFA) is a microprotein that inhibits of SR Ca 2+ pump (SERCA). wt hMLN plays an important role in skeletal muscle calcium homeostasis .
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- HY-105168
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Endothelin Receptor
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Cardiovascular Disease
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TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
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- HY-P4062
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BIL
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Insulin Receptor
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Metabolic Disease
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Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins .
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- HY-P4890A
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- HY-P10002A
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- HY-P5201S1
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Isotope-Labeled Compounds
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Others
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VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
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- HY-P10003A
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- HY-156341S1
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- HY-156343S1
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- HY-156345S1
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- HY-156344S1
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- HY-P1372
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PKC
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Others
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PKC ζ pseudosubstrate, a PKC ζ inhibitor peptide, can be attached to cell permeabilization vector peptide .
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- HY-P1371
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KKWKMRRNQFWIKIQRC CSVEIWD*
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PKC
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Others
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Pseudo RACK1, a peptide, is a PKC agonist with homologous sequences of PKC. Pseudo RACK1 interacts selectively with β-PKC at an autoregulatory site (RACK-binding site) and activates it in the absence of PKC activators, following inducing PKC-mediated histone phosphorylation .
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- HY-P1426A
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Potassium Channel
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Neurological Disease
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AmmTX3 TFA is a peptide toxin identified from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is a highly specific blocker of Kv4 channels, which selectively and almost completely blocks transient A-type K + currents with a Ki of 131 nM. AmmTX3 TFA induces epileptiform behaviors and causes death in mice receiving intracerebroventricular injection. AmmTX3 TFA increases the excitability of dentate gyrus granule cells, reduces GABAergic inhibition, enhances and stabilizes the EPSP-spike component of long-term potentiation, and impairs reference memory. AmmTX3 TFA can be used in research related to pain, epilepsy, and autism spectrum disorder .
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- HY-P11548
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Bacterial
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Infection
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Rattusin is an antimicrobial peptide. Rattusin exerts bactericidal activity by damaging membrane integrity. Rattusin can be used for antimicrobial research .
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- HY-P11625
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RXFP Receptor
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Cardiovascular Disease
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R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
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- HY-P3479
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|
|
Insulin Receptor
|
Metabolic Disease
|
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Insulin (swine) is an orally active insulin derived from pigs. Insulin (swine) when administered orally acts as an antigen to reduce the severity of pancreatic lymphocyte infiltration, but has no metabolic effect on blood glucose levels. Insulin (swine) increases glucose oxidation, stimulates lipogenesis, and lowers blood glucose levels. Insulin (swine) can be used in diabetes research .
|
-
- HY-P1925A
-
|
|
PI3K
Reactive Oxygen Species (ROS)
Apoptosis
|
Cancer
|
|
GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
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- HY-P3469A
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|
|
GCGR
|
Metabolic Disease
|
|
Dasiglucagon acetate is a human glucagon analog, and can increase plasma glucose. Dasiglucagon can be used in hypoglycemia research .
|
-
- HY-P3432
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
|
-
- HY-145632A
-
|
ALT-801 TFA
|
GLP Receptor
GCGR
|
Metabolic Disease
|
|
Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .
|
-
- HY-P10204
-
|
|
Wnt
|
Cancer
|
|
FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC50 value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .
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- HY-P2512A
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ペプチド
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Others
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Phytochelatin 2 (PC2) TFA is a phytochelatin, an important heavy metal-binding peptide. Phytochelatin 2 (PC2) TFA can chelate metals, prevent metal toxicity, and maintain metal stability in the internal environment .
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- HY-P11361
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ペプチド
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Metabolic Disease
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Des B30 Insulin is a bioactive insulin analogue lacking the B30 amino acid residue. Des B30 Insulin can be used for the study of diabetes .
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- HY-P4890
-
-
- HY-P10693
-
-
- HY-P11246
-
|
|
RXFP Receptor
|
Metabolic Disease
|
|
A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a Ki value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (Ki = 602.56 nM) and an inhibitory effect on cAMP (EC50) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC50 of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .
|
-
- HY-P6013A
-
|
|
Calcium Channel
|
Others
|
|
wt hMLN (TFA) is a microprotein that inhibits of SR Ca 2+ pump (SERCA). wt hMLN plays an important role in skeletal muscle calcium homeostasis .
|
-
- HY-105168
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
- HY-P4062
-
|
BIL
|
Insulin Receptor
|
Metabolic Disease
|
|
Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins .
|
-
- HY-P4890A
-
-
- HY-P10002A
-
-
- HY-P5201S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
|
-
- HY-P10003A
-
-
- HY-156341S1
-
-
- HY-156343S1
-
-
- HY-156345S1
-
-
- HY-156344S1
-
-
- HY-P1372
-
|
|
PKC
|
Others
|
|
PKC ζ pseudosubstrate, a PKC ζ inhibitor peptide, can be attached to cell permeabilization vector peptide .
|
-
- HY-P1371
-
|
KKWKMRRNQFWIKIQRC CSVEIWD*
|
PKC
|
Others
|
|
Pseudo RACK1, a peptide, is a PKC agonist with homologous sequences of PKC. Pseudo RACK1 interacts selectively with β-PKC at an autoregulatory site (RACK-binding site) and activates it in the absence of PKC activators, following inducing PKC-mediated histone phosphorylation .
|
-
- HY-P10014
-
-
- HY-P1426A
-
|
|
Potassium Channel
|
Neurological Disease
|
|
AmmTX3 TFA is a peptide toxin identified from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is a highly specific blocker of Kv4 channels, which selectively and almost completely blocks transient A-type K + currents with a Ki of 131 nM. AmmTX3 TFA induces epileptiform behaviors and causes death in mice receiving intracerebroventricular injection. AmmTX3 TFA increases the excitability of dentate gyrus granule cells, reduces GABAergic inhibition, enhances and stabilizes the EPSP-spike component of long-term potentiation, and impairs reference memory. AmmTX3 TFA can be used in research related to pain, epilepsy, and autism spectrum disorder .
|
-
- HY-P11548
-
|
|
Bacterial
|
Infection
|
|
Rattusin is an antimicrobial peptide. Rattusin exerts bactericidal activity by damaging membrane integrity. Rattusin can be used for antimicrobial research .
|
-
- HY-P11625
-
|
|
RXFP Receptor
|
Cardiovascular Disease
|
|
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
|
-
- HY-P5201S1
-
|
|
|
VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
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- HY-156341S1
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LLIYYTSSLHSGVPSR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
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- HY-156343S1
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SNNYATHYAESVK-(Lys- 13C6, 15N2) (TFA) is the peptide containing 13C- and 15N-labeled Lys.
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- HY-156345S1
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LPFTFGQGTK-(Lys- 13C6, 15N2) TFA is the peptide containing 13C- and 15N-labeled Lys.
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- HY-156344S1
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GLEWVAEIR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
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入力情報は安全に管理されます. ※ 必須入力項目.
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