A13:B7-24-GG
A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a Ki value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (Ki = 602.56 nM) and an inhibitory effect on cAMP (EC50) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC50 of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation.
For research use only. We do not sell to patients.
- CAS No.: 3057097-31-8
- Formula: C149H236N40O47S5
- Molecular Weight:3500.03
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 3057097-31-8
-
Molecular Weight 3500.03
-
Formula C149H236N40O47S5
-
Sequence
Chain1:Cys-Thr-Asp-Gly-Ala-Ser-Met-Lys-Asp-Leu-Ser-Ala-Leu-Cys Chain2:Cys-Gly-Leu-Glu-Tyr-Ile-Arg-Thr-Val-Ile-Tyr-Ile-Cys-Gly-Gly-Ser-Arg-Trp (Disulfidebridge:Chain 1 Cys1-Chain 2 Cys1, Chain 1 Cys14-Chain 2 Cys13)
-
Sequence Shortening
CTDGASMKDLSALC CGLEYIRTVIYICGGSRW (Disulfidebridge:Chain 1 Cys1-Chain 2 Cys1, Chain 1 Cys14-Chain 2 Cys13)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A13:B7-24-GG Related Classifications
HY-P11246 Related Classifications
Powered by Bioz