VTSEGAGLQLQK-13C6,15N2 TFA
VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect.
For research use only. We do not sell to patients.
- Formula: C4613C6H91N1315N2O19.xC2HF3O2
- Molecular Weight:1238.31 (free acid)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Molecular Weight 1238.31 (free acid)
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Formula C4613C6H91N1315N2O19.xC2HF3O2
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SMILES
O=C(C(F)(F)F)O.O=C([C@@H](N)C(C)C)N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C([15NH][13C@H]([13C](O)=O)[13CH2][13CH2][13CH2][13CH2][15NH2])=O)CCC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CC(C)C)=O)=O)C)=O)=O)CCC(O)=O)=O)CO)=O)[C@@H](C)O.[x]
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Sequence
Val-Thr-Ser-Glu-Gly-Ala-Gly-Leu-Gln-Leu-Gln-{Lys-13C6,15N2} (TFA salt)
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Sequence Shortening
VTSEGAGLQLQ-{Lys-13C6,15N2} (TFA salt)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)