OS-3-106
Based on 1 Customer Validation
OS-3-106 is a potent, and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 can be used for psychoactivator addiction research.
For research use only. We do not sell to patients.
- Purity: 97.03%
- CAS No.: 1580000-17-4
- Formula: C25H30N4O2S
- Molecular Weight:450.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Dopamine Receptor Isoforms
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Biological Activity
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D3 Receptor 0.2 nM (Ki) |
D2 Receptor |
OS-3-106 exhibits 115-fold binding selectivity for the D3R compared with the D2R[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1580000-17-4
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Appearance Solid
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Molecular Weight 450.60
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Formula C25H30N4O2S
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Color Off-white to light yellow
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SMILES
O=C(NCCCCN1CCN(C2=CC=CC=C2OC)CC1)C3=CC=C(C4=CSC=N4)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 83.33 mg/mL (184.93 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2193 mL | 11.0963 mL | 22.1926 mL | 55.4816 mL |
| 5 mM | 0.4439 mL | 2.2193 mL | 4.4385 mL | 11.0963 mL | |
| 10 mM | 0.2219 mL | 1.1096 mL | 2.2193 mL | 5.5482 mL | |
| 15 mM | 0.1480 mL | 0.7398 mL | 1.4795 mL | 3.6988 mL | |
| 20 mM | 0.1110 mL | 0.5548 mL | 1.1096 mL | 2.7741 mL | |
| 25 mM | 0.0888 mL | 0.4439 mL | 0.8877 mL | 2.2193 mL | |
| 30 mM | 0.0740 mL | 0.3699 mL | 0.7398 mL | 1.8494 mL | |
| 40 mM | 0.0555 mL | 0.2774 mL | 0.5548 mL | 1.3870 mL | |
| 50 mM | 0.0444 mL | 0.2219 mL | 0.4439 mL | 1.1096 mL | |
| 60 mM | 0.0370 mL | 0.1849 mL | 0.3699 mL | 0.9247 mL | |
| 80 mM | 0.0277 mL | 0.1387 mL | 0.2774 mL | 0.6935 mL | |
| 100 mM | 0.0222 mL | 0.1110 mL | 0.2219 mL | 0.5548 mL |