1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. OS-3-106

OS-3-106 

Cat. No.: HY-116820
Handling Instructions

OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 reduces cocaine self-administration and sucrose reinforcement rates. OS-3-106 can be used for psychostimulant addiction research.

For research use only. We do not sell to patients.

OS-3-106 Chemical Structure

OS-3-106 Chemical Structure

CAS No. : 1580000-17-4

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Description

OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 reduces cocaine self-administration and sucrose reinforcement rates. OS-3-106 can be used for psychostimulant addiction research[1].

IC50 & Target

D3 Receptor

0.2 nM (Ki)

D2 Receptor

 

In Vitro

OS-3-106 exhibits 115-fold binding selectivity for the D3R compared with the D2R[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

450.60

Formula

C25H30N4O2S

CAS No.
SMILES

O=C(NCCCCN1CCN(C2=CC=CC=C2OC)CC1)C3=CC=C(C4=CSC=N4)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
OS-3-106
Cat. No.:
HY-116820
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