1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. (R)-Lercanidipine hydrochloride

(R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a calcium channel blocker.

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(R)-Lercanidipine hydrochloride

(R)-Lercanidipine hydrochloride Estructura química

No. CAS : 187731-34-6

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100 mg   Obtener un presupuesto  

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Descripciòn

(R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a calcium channel blocker[1].

IC50 & Target

calcium channel[1]

Peso molecular

648.19

Fòrmula

C36H42ClN3O6

No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(OC(C)(CN(C)CCC(C1=CC=CC=C1)C2=CC=CC=C2)C)C3=C(NC(C)=C([C@H]3C4=CC=CC([N+]([O-])=O)=C4)C(OC)=O)C.[H]Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 25 mg/mL (38.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5428 mL 7.7138 mL 15.4276 mL
5 mM 0.3086 mL 1.5428 mL 3.0855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5428 mL 7.7138 mL 15.4276 mL 38.5689 mL
5 mM 0.3086 mL 1.5428 mL 3.0855 mL 7.7138 mL
10 mM 0.1543 mL 0.7714 mL 1.5428 mL 3.8569 mL
15 mM 0.1029 mL 0.5143 mL 1.0285 mL 2.5713 mL
20 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.9284 mL
25 mM 0.0617 mL 0.3086 mL 0.6171 mL 1.5428 mL
30 mM 0.0514 mL 0.2571 mL 0.5143 mL 1.2856 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
(R)-Lercanidipine hydrochloride
Cat. No.:
HY-B0612D
Cantidad:
MCE Japan Authorized Agent: