1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. Lercanidipine hydrochloride

Lercanidipine hydrochloride 

Cat. No.: HY-B0612A Purity: 98.50%
Handling Instructions

Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.

For research use only. We do not sell to patients.

Lercanidipine hydrochloride Chemical Structure

Lercanidipine hydrochloride Chemical Structure

CAS No. : 132866-11-6

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
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50 mg USD 190 In-stock
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100 mg USD 290 In-stock
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200 mg USD 390 In-stock
Estimated Time of Arrival: December 31
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Description

Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class. Target: Calcium Channel Lercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. Lercanidipine was effective and well-tolerated in patients with mild-to-moderate hypertension in the daily practice. The effectiveness and safety of the drug were independent of the degree of cardiovascular risk [1, 2].

Molecular Weight

648.19

Formula

C₃₆H₄₂ClN₃O₆

CAS No.

132866-11-6

SMILES

O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OC(C)(C)CN(CCC(C3=CC=CC=C3)C4=CC=CC=C4)C.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (77.14 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5428 mL 7.7138 mL 15.4276 mL
5 mM 0.3086 mL 1.5428 mL 3.0855 mL
10 mM 0.1543 mL 0.7714 mL 1.5428 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (3.86 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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Keywords:

LercanidipineCalcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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Product name:
Lercanidipine hydrochloride
Cat. No.:
HY-B0612A
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