2. Others GPCR/G Protein Stem Cell/Wnt MAPK/ERK Pathway Neuronal Signaling
  3. Adrenergic Receptor Isotope-Labeled Compounds ERK
  4. Salbutamol-d3

Salbutamol-d3  (Synonyms: Albuterol-d3; AH-3365-d3)

Art. -Nr.: HY-B1037S Reinheit: 98.59%
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Handling Instructions Technical Support

Salbutamol-d3 (Albuterol-d3) is the deuterium labeled Salbutamol (HY-B1037). Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease.

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Salbutamol-d<sub>3</sub>

Salbutamol-d3 Chemische Struktur

CAS. Nr. : 1219798-60-3

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Other Forms of Salbutamol-d3:

Salbutamol-d3 Related Antibodies

Top Publications Citing Use of Products

Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
α adrenergic receptor β adrenergic receptor

Alle ERK Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
ERK ERK1 ERK2 ERK5 ERK8

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Beschreibung

Salbutamol-d3 (Albuterol-d3) is the deuterium labeled Salbutamol (HY-B1037). Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Salbutamol-d3 Related Antibodies
Molekulargewicht

242.33

Formel

C13H18D3NO3
CAS. Nr.
Unlabeled CAS
Appearance

Solid

Color

Off-white to light brown

SMILES

OC([2H])([2H])C1=C(O)C=CC(C(CNC(C)(C)C)([2H])O)=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (412.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1266 mL 20.6330 mL 41.2660 mL
5 mM 0.8253 mL 4.1266 mL 8.2532 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1266 mL 20.6330 mL 41.2660 mL 103.1651 mL
5 mM 0.8253 mL 4.1266 mL 8.2532 mL 20.6330 mL
10 mM 0.4127 mL 2.0633 mL 4.1266 mL 10.3165 mL
15 mM 0.2751 mL 1.3755 mL 2.7511 mL 6.8777 mL
20 mM 0.2063 mL 1.0317 mL 2.0633 mL 5.1583 mL
25 mM 0.1651 mL 0.8253 mL 1.6506 mL 4.1266 mL
30 mM 0.1376 mL 0.6878 mL 1.3755 mL 3.4388 mL
40 mM 0.1032 mL 0.5158 mL 1.0317 mL 2.5791 mL
50 mM 0.0825 mL 0.4127 mL 0.8253 mL 2.0633 mL
60 mM 0.0688 mL 0.3439 mL 0.6878 mL 1.7194 mL
80 mM 0.0516 mL 0.2579 mL 0.5158 mL 1.2896 mL
100 mM 0.0413 mL 0.2063 mL 0.4127 mL 1.0317 mL
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Salbutamol-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Salbutamol-d31219798-60-3Albuterol-d3AH-3365-d3Adrenergic ReceptorIsotope-Labeled CompoundsERKBeta ReceptorExtracellular signal regulated kinasesInhibitorinhibitorinhibit

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