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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Aspartyl protease
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Aspartyl protease" in MCE Product Catalog:
6
Target:
Research Areas:
L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI). L-685458 inhibits amyloid β-protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. L685458 inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100 with IC50s of 301.3 nM and 351.3 nM, respectively. L-685458 can be used for the research of alzheimer’s disease (AD) and cancers .
1
1 Cited Publications
Cat. No.: HY-P72155
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CTSD; Cathepsin D (Lysosomal Aspartyl protease); Prev. CPSD; Lysosomal Aspartyl protease; CLN10; Cathepsin D Isoform 2; Ceroid-Lipofuscinosis, Neuronal 10; HEL-S-130P; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D; Lysosomal Aspartyl Pep
1
1 Cited Publications
Cat. No.: HY-P7748A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSD; Cathepsin D (Lysosomal Aspartyl protease); Prev. CPSD; Lysosomal Aspartyl protease; CLN10; Cathepsin D Isoform 2; Ceroid-Lipofuscinosis, Neuronal 10; HEL-S-130P; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D; Lysosomal Aspartyl Pep
1
1 Cited Publications
Cat. No.: HY-P7748
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSD; Cathepsin D (Lysosomal Aspartyl protease); Prev. CPSD; Lysosomal Aspartyl protease; CLN10; Cathepsin D Isoform 2; Ceroid-Lipofuscinosis, Neuronal 10; HEL-S-130P; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D; Lysosomal Aspartyl Pep
Cat. No.: HY-178374
Target:
Research Areas:
BACE-1/Mpro-IN-1 is a high brain-penetrant BACE-1 (IC50 = 0.26 μM) and SARS-CoV-2 Mpro (IC50 = 0.91 μM) dual inhibitor. BACE-1/Mpro-IN-1 binds to the aspartyl protease and cysteine protease as a mixed-type inhibitor. BACE-1/Mpro-IN-1 exhibits the most favorable docking score and a strong interaction profile. BACE-1/Mpro-IN-1 can be used for the study of COVID-19 exacerbated Neuroinflammation and Alzheimer’s disease .
Cat. No.: HY-P7749
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSD; Cathepsin D (Lysosomal Aspartyl protease); Prev. CPSD; Lysosomal Aspartyl protease; CLN10; Cathepsin D Isoform 2; Ceroid-Lipofuscinosis, Neuronal 10; HEL-S-130P; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D; Lysosomal Aspartyl Pep
Cat. No.: HY-P706171
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CTSD; Cathepsin D (Lysosomal Aspartyl protease); Prev. CPSD; Lysosomal Aspartyl protease; CLN10; Cathepsin D Isoform 2; Ceroid-Lipofuscinosis, Neuronal 10; HEL-S-130P; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D; Lysosomal Aspartyl Pep
Cat. No.: HY-187058
CAS No.: 158268-42-9
Target:
Research Areas:
MDL-104168 is a macrocyclic peptide mimetic HIV protease inhibitor (human IC50: 2 nM; Ki: 20 nM). MDL-104168 can be used for the research of human immunodeficiency virus infection .
Cat. No.: HY-182316
CAS No.: 449806-40-0
Target:
Research Areas:
P-1946 is a HIV protease inhibitor with a human HIV-1 protease Ki of 2.600 nM. P-1946 has potent and selective in vitro antiviral activity and retains full antiviral activity against HIV isolates resistant to commercially available protease inhibitors. P-1946 can be used for the research of human immunodeficiency virus type 1 (HIV-1) infection .
Cat. No.: HY-P72840
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-Secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl protease 2; Transmembrane Aspartic Prot
Cat. No.: HY-P82169
Synonyms: BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
Cat. No.: HY-P86180
Synonyms: BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
Cat. No.: HY-P85420
Synonyms: BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
Cat. No.: HY-P72843
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-Secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl protease 2; Transmembrane Aspartic Prot
Cat. No.: HY-P700606
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-Secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl protease 2; Transmembrane Aspartic Prot
Cat. No.: HY-P72842
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-Secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl protease 2; Transmembrane Aspartic Prot
Cat. No.: HY-P77569
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-Secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl protease 2; Transmembrane Aspartic Prot
Cat. No.: HY-P704472
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-Secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl protease 2; Transmembrane Aspartic Prot
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
