Bee

By Targets:	5-HT Receptor (1) Acyltransferase (1) Bacterial (2) Biochemical Assay Reagents (1) Endogenous Metabolite (2) GABA Receptor (1) Histamine Receptor (1) Isotope-Labeled Compounds (2) nAChR (1) Parasite (1) Potassium Channel (2)
By Research Areas:	Cancer (1) Endocrinology (2) Infection (4) Inflammation/Immunology (4) Neurological Disease (6)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1363

Royal Jelly acid 2 Publications Verification Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid	Endogenous Metabolite	Neurological Disease
Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes .

HY-N1363R

Royal Jelly acid (Standard) Queen Bee Acid (Standard); (E)-10-Hydroxy-2-decenoic acid (Standard)	Endogenous Metabolite	Neurological Disease
Royal Jelly acid (Standard) is the analytical standard of Royal Jelly acid. This product is intended for research and analytical applications. Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes .

HY-133968

24-Methylenecholesterol Ostreasterol	Acyltransferase	Inflammation/Immunology
24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

HY-N0073A

Spirostan-3-ol

Others Others

Spirostan-3-ol is a useful tool to keep bees away from areas recently treated with toxic insecticides .

Spirostan-3-ol	Others	Others
Spirostan-3-ol is a useful tool to keep bees away from areas recently treated with toxic insecticides .

HY-P5629

MCF	Bacterial	Infection
MCF is an antimicrobial peptide derived from bee venom. MCF has activity against E.coli W 160-37, S.aureus 8530 and B.subtilis, the MIC values are 35-45 μg/ml, 25-35 μg/ml and 15-25 μg/ml .

HY-128030

Makisterone A

Others Endocrinology

Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .
HY-N8491A

(+)-Dihydrocarvone

Others Others

(+)-Dihydrocarvone elicits strong antennal responses of A. mellifera. (+)-Dihydrocarvone influences bee foraging preference for tomato .
HY-13211

(E)-2-Decenoic acid

trans-2-Decenoic acid
Others Cancer

(E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.
HY-N9512

Lycopsamine N-oxide

Others Others

Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen .

Makisterone A	Others	Endocrinology
Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .

(+)-Dihydrocarvone	Others	Others
(+)-Dihydrocarvone elicits strong antennal responses of A. mellifera. (+)-Dihydrocarvone influences bee foraging preference for tomato .

(E)-2-Decenoic acid trans-2-Decenoic acid	Others	Cancer
(E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.

Lycopsamine N-oxide	Others	Others
Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen .

HY-133968S1

24-Methylenecholesterol-13C Ostreasterol-¹³C	Isotope-Labeled Compounds	Others
24-Methylenecholesterol- ¹³C (Ostreasterol- ¹³C)is the ¹³C labeled24-Methylenecholesterol(HY-133968) . 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

HY-12537

Peptide 401	Histamine Receptor 5-HT Receptor	Inflammation/Immunology Endocrinology
Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).

HY-N9512S

Lycopsamine N-oxide-d3	Isotope-Labeled Compounds	Others
Lycopsamine N-oxide-d₃ is the deuterium labeled Lycopsamine N-oxide. Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen[1].

HY-P0256

Apamin 3 Publications Verification Apamine	Potassium Channel	Neurological Disease Inflammation/Immunology
Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca ²⁺-activated K ⁺ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .

HY-P0256A

Apamin TFA 3 Publications Verification Apamine TFA	Potassium Channel	Neurological Disease Inflammation/Immunology
Apamin TFA (Apamine TFA) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca ²⁺-activated K ⁺ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .

HY-P3914

Cecropin A (1-7)-Melittin A (2-9) Oct-CA(1-7)M(2-9)	Bacterial	Infection
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .

HY-125744

Palmitoyl thio-PC	Biochemical Assay Reagents	Others
Palmitoyl thio-PC is a chromogenic substrate specific for PLA2 with a palmitoyl thioester at the sn-2 position. Palmitoyl thio-PC could be used to measure bee-venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system .

HY-N2927

Costic acid β-Costic acid	Parasite	Infection
Costic acid (β-Costic acid) is a natural product, that can be isolated from Dittrichia viscosa. Costic acid exhibits potent in vivo acaricidal activity against the parasite. Costic acid is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 μM. Costic acid can be used for the research of varroosis in honey bee colonies .

HY-103474

Bicuculline methiodide (+)-Bicuculline methiodide; d-Bicuculline methiodide	GABA Receptor	Neurological Disease
Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca ²⁺ -activated K ⁺ channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca ²⁺ -activated K ⁺ current .

HY-145295

Flupyradifurone	nAChR	Infection
Flupyradifurone is a systemic nAChR agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide insecticide .

Cat. No.	Product Name	Target	Research Area

HY-12537

Peptide 401	Histamine Receptor 5-HT Receptor	Inflammation/Immunology Endocrinology
Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).

HY-P0256

Apamin 3 Publications Verification Apamine	Potassium Channel	Neurological Disease Inflammation/Immunology
Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca ²⁺-activated K ⁺ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .

HY-P0256A

Apamin TFA 3 Publications Verification Apamine TFA	Potassium Channel	Neurological Disease Inflammation/Immunology
Apamin TFA (Apamine TFA) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca ²⁺-activated K ⁺ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .

HY-P5629

MCF	Bacterial	Infection
MCF is an antimicrobial peptide derived from bee venom. MCF has activity against E.coli W 160-37, S.aureus 8530 and B.subtilis, the MIC values are 35-45 μg/ml, 25-35 μg/ml and 15-25 μg/ml .

HY-P1987

Mast cell degranulating peptide (28-49)	Peptides	Neurological Disease
Mast cell degranulating peptide (28-49) is a depolarizing agent from bee venom, it can raise the content of cGMP level in mouse cerebellar slices .

HY-P3914

Cecropin A (1-7)-Melittin A (2-9) Oct-CA(1-7)M(2-9)	Bacterial	Infection
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1363

Royal Jelly acid 2 Publications Verification Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid	Animals Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes .

HY-128030

Makisterone A	Classification of Application Fields Source classification Chenopodium quinoa Willd. Plants Disease Research Fields Endocrinology Steroids Chenopodiaceae	Others
Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .

HY-N1363R

Royal Jelly acid (Standard) Queen Bee Acid (Standard); (E)-10-Hydroxy-2-decenoic acid (Standard)	Structural Classification Animals Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Royal Jelly acid (Standard) is the analytical standard of Royal Jelly acid. This product is intended for research and analytical applications. Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes .

HY-133968

24-Methylenecholesterol Ostreasterol	Structural Classification Classification of Application Fields Anti-aging Source classification Marine natural products Other marine organisms Plants other families Microorganisms Animals Inflammation/Immunology Disease Research Fields Steroids	Acyltransferase
24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

HY-N0073A

Spirostan-3-ol	other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Steroids	Others
Spirostan-3-ol is a useful tool to keep bees away from areas recently treated with toxic insecticides .

HY-N8491A

(+)-Dihydrocarvone	Structural Classification Endopappus macrocarpus Sch.Bip. Terpenoids Labiatae Sesquiterpenes Source classification Plants	Others
(+)-Dihydrocarvone elicits strong antennal responses of A. mellifera. (+)-Dihydrocarvone influences bee foraging preference for tomato .

HY-N9512

Lycopsamine N-oxide	Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen .

HY-P1987

Mast cell degranulating peptide (28-49)	Natural Products Animals Source classification	Others
Mast cell degranulating peptide (28-49) is a depolarizing agent from bee venom, it can raise the content of cGMP level in mouse cerebellar slices .

HY-N2927

Costic acid β-Costic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Compositae Desmodium sandwicense	Parasite
Costic acid (β-Costic acid) is a natural product, that can be isolated from Dittrichia viscosa. Costic acid exhibits potent in vivo acaricidal activity against the parasite. Costic acid is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 μM. Costic acid can be used for the research of varroosis in honey bee colonies .

Cat. No.	Product Name	Chemical Structure

HY-133968S1

24-Methylenecholesterol-13C
24-Methylenecholesterol- ¹³C (Ostreasterol- ¹³C)is the ¹³C labeled24-Methylenecholesterol(HY-133968) . 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

HY-N9512S

Lycopsamine N-oxide-d3
Lycopsamine N-oxide-d₃ is the deuterium labeled Lycopsamine N-oxide. Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen[1].

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